SAB3300047

モノクローナル抗TUBB3抗体 マウス宿主抗体

clone 5H2, purified immunoglobulin, buffered aqueous glycerol solution

• 別名: 抗β-4抗体, 抗MC1R抗体, 抗TUBB4抗体
• UNSPSCコード: 12352203

特性

• 由来生物: mouse
• 結合体: unconjugated
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 5H2, monoclonal
• 形状: buffered aqueous glycerol solution
• 分子量: antigen 50.3 kDa
• 化学種の反応性: human
• テクニック: western blot: suitable
• NCBIアクセッション番号: NM_006086
• UniProtアクセッション番号: Q13509
• 輸送温度: dry ice
• 保管温度: −20°C
• 遺伝子情報: human ... TUBB3(10381)

詳細

免疫原

E. coliで発現させたヒトTUBB3のアミノ酸1-150に相当するリコンビナントタンパク質

ターゲットの説明

Tubulin is the major building block of microtubules. This intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules function as structural and mobile elements in mitosis, intracellular transport, flagellar movement, and the cytoskeleton. Except in the simplest eukaryotes, tubulin exists in all cells as a mixture of similar, but not identical, sets of alpha and beta tubulin polypeptides. Within either set of polypeptides, individual subunits diverge from each other (both within and across species) at less than 10% of the amino acid positions. The most extreme diversity is localized to the 15 residues of the carboxy terminal. For β-tubulin five evolutionarily conserved isotype clones have been identified. These are almost totally conserved in the subunits utilized in the same cell types of different species, with the exception of the hematopoietic β-tubulin which is the most highly divergent in sequence and is not conserved between species. Research has been centered around the hypothesis that these beta tubulin isotypes contribute to unique functional properties. It has been reported that the different isotypes of tubulin differ from each other in their ability to polymerize into microtubules.

物理的形状

PBS溶液(1% BSA, 50%グリセロール, 0.02%アジ化ナトリウム含有)。

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable