Asporin (ASPN) is an extracellular matrix (ECM) macromolecule. It is encoded by the gene mapped to human chromosome 9q22.31. ASPN is a member of small leucine-rich proteoglycan (SLRP) family.
Asporin (ASPN) plays a vital role in regulation of chondrogenesis and helps to maintain the cartilage matrix. ASPN also facilitates transforming growth factor (TGF)-f-mediated signaling. It stimulates osteoblast collagen mineralization by interacting with collagen and calcium. Mutation in the gene is associated with the development of acetabular dysplasia (AD) and hip osteoarthritis.
特徴および利点
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物理的形状
0.5 mg/mL Tris緩衝生理食塩水(0.5% BSA, 0.02%アジ化ナトリウム含有)。
免責事項
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