S6936

抗ナトリウムチャネル, Pan ウサギ宿主抗体

affinity isolated antibody, lyophilized powder

• 別名: 抗SP19抗体
• MDL番号: MFCD02097413
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: lyophilized powder
• 化学種の反応性: rat
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; immunoprecipitation (IP): suitable; western blot (chemiluminescent): 1:200-1:600
• UniProtアクセッション番号: P04774
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: rat ... Scn1a(81574)

詳細

詳細

Voltage-gated sodium channels (VGSC) are membrane proteins that are usually present in excitable cells. These sodium channels regulate neurological functions such as the generation of action potentials in nerve cells. Alterations in neurological sodium ion channels have been associated with epilepsy, whereas mutations in cardiac sodium channels have been linked to long QT syndrome . Anti-Sodium Channel, Pan antibody is specific for the α subunit of VGSC in rats.

免疫原

ラットI 型電位依存性 ナトリウムチャネル(VGSC, SP19) αサブユニットのアミノ酸1491-1508(C末端システイン付加)に相当する合成ペプチド。エピト-プはVGSCαサブユニットのドメインIIIとIVの間の細胞内ル-プにある配列に相当し、脊椎動物で同一、軟体動物や昆虫で高い相同性を示します。

アプリケーション

Anti-Sodium Channel, Pan antibody is suitable for use in immunohistochemistry (formalin-fixed, paraffin-embedded sections), immunoprecipitation and chemiluminescent western blot.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunohistochemistry (1 paper)

物理的形状

凍結乾燥品 (PBS, pH 7.4, 1%BSA, 0.05%アジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H302 + H332,H311,H412
• 注意書き: P273 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable