R8900

Ro 8-4304

solid

• 実験式（ヒル表記法）: C₂₁H₂₃FN₂O₃ · HCl
• 分子量: 406.88
• MDL番号: MFCD03101333
• UNSPSCコード: 12352200
• PubChem Substance ID: 24277971
• NACRES: NA.77

特性

• フォーム: solid
• 品質水準: 100
• 溶解性: H₂O: ≤0.5 mg/mL
• オーガナイザー: Roche
• 保管温度: 2-8°C
• SMILES記法: Cl.NC(=O)c1ccc(OCCC(O)N2CCC(=CC2)c3ccc(F)cc3)cc1
• InChI: 1S/C21H23FN2O3.ClH/c22-18-5-1-15(2-6-18)16-9-12-24(13-10-16)20(25)11-14-27-19-7-3-17(4-8-19)21(23)26;/h1-9,20,25H,10-14H2,(H2,23,26);1H
• InChI Key: NYFXHCMXYODFLP-UHFFFAOYSA-N
• 遺伝子情報: human ... GRIN2B(2904)

詳細

生物化学的／生理学的作用

NR2B-selective, noncompetitive NMDA glutamate receptor antagonist

特徴および利点

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves