P1851

PIPES

BioPerformance Certified, suitable for cell culture

• 別名: 1,4-ピペラジンジエタンスルホン酸, ピペラジン-1,4-ビス(2-エタンスルホン酸), ピペラジン-N,N′-ビス(2-エタンスルホン酸)
• 実験式（ヒル表記法）: C₈H₁₈N₂O₆S₂
• CAS番号: 5625-37-6
• 分子量: 302.37
• Beilstein: 817713
• EC Number: 227-057-6
• MDL番号: MFCD00006159
• UNSPSCコード: 12161700
• PubChem Substance ID: 24898249
• NACRES: NA.25

特性

• グレード: BioPerformance Certified; for molecular biology
• 形状: crystalline powder
• テクニック: cell culture | mammalian: suitable
• 不純物: endotoxin and Total Aerobic Microbial Count, tested
• 有効pH範囲: 6.1-7.5
• pKa (25 °C): 6.8
• mp: >300 °C (lit.)
• 溶解性: 1 M NaOH: 20 + 80 mL g, clear, colorless; soluble
• アプリケーション: diagnostic assay manufacturing
• その他の活性: DNAse, Exonuclease; NICKase, Endonuclease; RNAse; Protease, none detected
• SMILES記法: OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O
• InChI: 1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
• InChI Key: IHPYMWDTONKSCO-UHFFFAOYSA-N

詳細

アプリケーション

• Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics.: The use of PIPES buffer in this study was integral to maintaining the stability of immunoglobulin G during differential scanning fluorimetry. This method is crucial for evaluating the stability of antibody-based therapeutics (Moggridge et al., 2017).

安全性情報

• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)