N9412

6β-Naltrexol hydrate

≥96% (HPLC), powder

• 別名: (5α,6β)-17-(Cyclopropylmethyl)-4,5-epoxy-morphinan-3,6,14-triol hydrate
• 実験式（ヒル表記法）: C₂₀H₂₅NO₄ · xH₂O
• CAS番号: 1034528-53-4
• 分子量: 343.42 (anhydrous basis)
• MDL番号: MFCD08277038
• UNSPSCコード: 12352200
• PubChem Substance ID: 24724560
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥96% (HPLC)
• 形状: powder
• 薬剤管理: regulated under CDSA - not available from Sigma-Aldrich Canada
• 色: white
• 溶解性: DMSO: ~12 mg/mL; H₂O: insoluble
• 保管温度: 2-8°C
• SMILES記法: [H]O[H].O[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC6CC6)c45
• InChI: 1S/C20H25NO4.H2O/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11;/h3-4,11,14-15,18,22-24H,1-2,5-10H2;1H2/t14-,15-,18+,19+,20-;/m1./s1
• InChI Key: VHGGWFVHXKTOPK-CDHBEYIESA-N

詳細

生物化学的／生理学的作用

Neutral antagonist of the μ-opioid receptor. A reduction of withdrawal effects associated with neutral μ-opioid receptor antagonists may offer advantages in treating opioid overdose and addiction.

特徴および利点

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)