MBD0001
Microbial DNA standard from Akkermansia muciniphila
Suitable for PCR, sequencing and NGS, 10 ng/μL
ログイン組織・契約価格を表示する
サイズを選択してください
0.3 μG
￥43,900
￥43,900
Check Cart for Availability
品質そのまま、お求めになりやすい価格になりました。メルクは皆さんの科学発展を支えるパートナーとして製品を提供します。
すべての画像(1)
サイズを選択してください
表示を変更する
0.3 μG
￥43,900
About This Item
UNSPSCコード:
41105500
NACRES:
NA.24
￥43,900
Check Cart for Availability
品質そのまま、お求めになりやすい価格になりました。メルクは皆さんの科学発展を支えるパートナーとして製品を提供します。
おすすめの製品
品質水準
フォーム
liquid
濃度
10 ng/μL
テクニック
DNA extraction: suitable
DNA sequencing: suitable
PCR: suitable
輸送温度
ambient
保管温度
−20°C
関連するカテゴリー
詳細
Standardization of sample analysis is currently needed in microbiome genomics research workflow. Lack of standardization can lead to biases and errors in common processes during sample preparation and analysis such as sample amplification, sequencing and bioinformatics analyses.1 Akkermansia muciniphila genomic DNA microbial standard can serve as standard for benchmarking the performance along the workflow of microbiomics or meta-genomics analyses and as a tool to increase reproducibility and allow comparison of results obtained by different labs.
Akkermansia muciniphila is a gram negative, anaerobic, non motile, non spore forming and oval shaped bacterium. A. muciniphila inhabits the gastrointestinal tracts of more than 90% of adults and constitutes 1 to 4% of the fecal microbiota.2 A. muciniphila level was suggested to be a biomarker for a healthy intestin. 3
A. muciniphila degrades mucus and utilizes it as a carbon/nitrogen source. Consequently, the host produces additional mucus while the bacterium produces oligosaccharides and Short Chain Fatty Acids (SCFAs) that can be utilized by the host and trigger the immune system. An additional protective effect of the SCFA is stimulation of mucus-associated microbiota growth, that serves as a barrier against penetration of pathogens to intestinal cells. 2,4
Read here how to use our standards to ensure data integrity for your microbiome research.
Akkermansia muciniphila is a gram negative, anaerobic, non motile, non spore forming and oval shaped bacterium. A. muciniphila inhabits the gastrointestinal tracts of more than 90% of adults and constitutes 1 to 4% of the fecal microbiota.2 A. muciniphila level was suggested to be a biomarker for a healthy intestin. 3
A. muciniphila degrades mucus and utilizes it as a carbon/nitrogen source. Consequently, the host produces additional mucus while the bacterium produces oligosaccharides and Short Chain Fatty Acids (SCFAs) that can be utilized by the host and trigger the immune system. An additional protective effect of the SCFA is stimulation of mucus-associated microbiota growth, that serves as a barrier against penetration of pathogens to intestinal cells. 2,4
Read here how to use our standards to ensure data integrity for your microbiome research.
アプリケーション
Suitable for Quantitative standard for PCR, Sequencing and NGS
特徴および利点
- Individual microbial standard for microbiomics and meta-genomics workflow
- Suitable standard for PCR, sequencing and NGS
- Improve Bioinformatics analyses
- Increases reproducibility
- Compare results lab to lab
物理的形状
Liquid - The genomic DNA is provided at ≥10 ng/μL concentration in TE buffer pH 8.0
その他情報
It is recommended to avoid freeze thaw cycles of this product.
保管分類コード
12 - Non Combustible Liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
MBD0001-BULK:
MBD0001-0.3UG:
MBD0001-VAR:
最新バージョンのいずれかを選択してください：
Muriel Derrien et al.
International journal of systematic and evolutionary microbiology, 54(Pt 5), 1469-1476 (2004-09-25)
The diversity of mucin-degrading bacteria in the human intestine was investigated by combining culture and 16S rRNA-dependent approaches. A dominant bacterium, strain MucT, was isolated by dilution to extinction of faeces in anaerobic medium containing gastric mucin as the sole
Clara Belzer et al.
The ISME journal, 6(8), 1449-1458 (2012-03-23)
The human intestinal tract is colonized by a myriad of microbes that have developed intimate interactions with the host. In healthy individuals, this complex ecosystem remains stable and resilient to stressors. There is significant attention on the understanding of the
Chin Wen Png et al.
The American journal of gastroenterology, 105(11), 2420-2428 (2010-07-22)
Mucosa-associated bacteria are increased in inflammatory bowel disease (IBD), which suggests the possibility of an increased source of digestible endogenous mucus substrate. We hypothesized that mucolytic bacteria are increased in IBD, providing increased substrate to sustain nonmucolytic mucosa-associated bacteria. Mucolytic
J Paul Brooks et al.
BMC microbiology, 15, 66-66 (2015-04-17)
Characterizing microbial communities via next-generation sequencing is subject to a number of pitfalls involving sample processing. The observed community composition can be a severe distortion of the quantities of bacteria actually present in the microbiome, hampering analysis and threatening the
資料
An overview of human microbiome research, workflow challenges, sequencing, library production, data analysis, and available microbiome reagents to support your research.
DNA standards enhance metagenomics research integrity, offering precise species study and mixed community standards.
アクティブなフィルタ
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）
