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安全性情報

MAK068

Sigma-Aldrich

MPO Colorimetric Activity Assay Kit

sufficient for 100 colorimetric tests

別名:

Myeloperoxidase Colorimetric Activity Assay Kit

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About This Item

UNSPSCコード:
12161503
NACRES:
NA.84
現在、価格および在庫状況を閲覧できません。

使用法

sufficient for 100 colorimetric tests

検出方法

colorimetric

関連疾患

cancer; cardiovascular diseases; hematological disorder

保管温度

−20°C

遺伝子情報

human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)

詳細

Myeloperoxidase (MPO) is a heme-containing enzyme that catalyzes the hydrogen peroxidase-mediated oxidation of halide ions to hypochlorous acid. MPO is a lysosomal protein, highly expressed in neutrophils, that plays a role in the antimicrobial actions that occur as a result of neutrophil stimulation. The actions of MPO may also contribute to the initiation and pathogenesis of cardiovascular disease.

アプリケーション

MPO Colorimetric Activity Assay Kit has been used to determine the activity of myeloperoxidase in samples.[1][2][3]

特徴および利点

Compatible with high-throughput handling systems.

適合性

Suitable for the measurement of myeloperoxidase (MPO) in biological samples such as tissue, cells, serum and white blood cells

原理

In this assay, MPO catalyzes the formation of hypochlorous acid, which reacts with taurine to form taurine chloroamine. Taurine chloroamine reacts with the chromophore TNB, resulting in the formation of the colorless product DTNB. One unit of MPO activity is defined as the amount of enzyme that hydrolyzes the substrate and generates taurine chloramine to consume 1.0 μmole of TNB per minute at 25 °C.

ピクトグラム

Health hazard
GHS08

シグナルワード

Danger

危険有害性情報

H315,H319,H334

危険有害性の分類

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2

保管分類コード

10 - Combustible liquids

引火点(°F)

188.6 °F

引火点(℃)

87 °C

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

毒物及び劇物取締法

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PRTR

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消防法

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労働安全衛生法名称等を表示すべき危険物及び有害物

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労働安全衛生法名称等を通知すべき危険物及び有害物

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カルタヘナ法

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Jan Code

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最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number
8F23K07440
7L08K07440
7G02K07440
7B17K07440
6L24K07440

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質問

1–3/3 質問  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 回答

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      役に立ちましたか？

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 回答

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      役に立ちましたか？

  3. Does hemoglobin interfere with the MAK068 MPO Colorimetric Activity Assay Kit?

    1 回答

    1. Hemoglobin is not known to cause interference. The sample background should account for any background signal other than the intended signal.

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