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由来生物
chicken
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
交差性
human
メーカー／製品名
Genway 15-288-22760
テクニック
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... STAT6(6778)
免疫原
Immunogen Sequence: GI # 23397678, sequence 61-275
Recombinant signal transducer and activator of transcription 6
アプリケーション
Anti-STAT6 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生物化学的／生理学的作用
STAT6 is a human gene and is a member of the STAT family of transcription factors. It is mapped to human chromosome band 12q13. STAT6 has the same functional domain for both receptor coupling and dimerization. It is highly expressed in comparison with the other STAT proteins. STAT-6 silencing results in the reduction of HeLa cell programmed death and the expression of several important key factors related to programmed cell death. It is a highly sensitive and specific marker of solitary fibrous tumor (SFT). It can also be helpful in distinguishing tumor type from histologic mimics.
物理的形状
Solution in phosphate buffered saline containing 0.02% sodium azide.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
GW22760-50UG:
GW22760-VAR:
GW22760-BULK:
最新バージョンのいずれかを選択してください：
Akihiko Yoshida et al.
The American journal of surgical pathology, 38(4), 552-559 (2014-03-15)
Solitary fibrous tumor (SFT) is an uncommon fibroblastic neoplasm. Although histologic characteristics and frequent CD34 expression allow for an accurate diagnosis in the majority of SFT cases, a wide histologic spectrum and an occasional unexpected immunophenotype may pose diagnostic challenges.
Leona A Doyle et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 27(3), 390-395 (2013-09-14)
Solitary fibrous tumor (SFT) is composed of spindled to ovoid cells in a patternless architecture with prominent stromal collagen and hemangiopericytoma-like vessels. Some tumors show hypercellularity, nuclear atypia, and significant mitotic activity; the latter feature in particular often portends an
Zhibin Li et al.
Biomaterials, 35(18), 5016-5027 (2014-03-29)
Based on the fact that the transcription of STAT-1 plus its Serine 727 and Tyrosine 701 phosphorylation is not the pre-requisite for the cell death signal transduction in the IFN-γ signaling pathway induced by co-immobilized IFN-γ/TNF-α, we investigate both in
Assignment of the STAT6 gene (STAT6) to human chromosome band 12q13 by in situ hybridization.
J P Leek et al.
Cytogenetics and cell genetics, 79(3-4), 208-209 (1997-01-01)
J Hou et al.
Science (New York, N.Y.), 265(5179), 1701-1706 (1994-09-16)
Interleukin-4 (IL-4) is an immunomodulatory cytokine secreted by activated T lymphocytes, basophils, and mast cells. It plays an important role in modulating the balance of T helper (Th) cell subsets, favoring expansion of the Th2 lineage relative to Th1. Imbalance
アクティブなフィルタ
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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