F6397

IgG1-FITCアイソタイプコントロール マウスミエローマ由来

clone MOPC 21, purified immunoglobulin, buffered aqueous solution

• 別名: IgG1アイソタイプコントロール マウスミエローマ由来
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: mouse
• 結合体: FITC conjugate
• 抗体製品の状態: purified immunoglobulin
• クローン: MOPC 21, monoclonal
• フォーム: buffered aqueous solution
• 保管条件: protect from light
• テクニック: flow cytometry: suitable
• 輸送温度: wet ice
• 保管温度: 2-8°C
• ターゲットの翻訳後修飾: unmodified

詳細

詳細

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody.[1] An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense.[2] It is a glycoprotein. IgG is a major class of immunoglobulin.[3] Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE.[3] Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.[4]

アプリケーション

IgG1-FITC Isotype Control from murine myeloma was used as negative control in FACS of human erythroid cell population that is expresses CD17.[5]

IgG1?FITC Isotype Control from murine myeloma has been used in flow cytometry[6] and as a negative staining control.[5]

生物化学的／生理学的作用

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.[7]

Immunoglobulin G (IgG) plays a major role in hypersensitivity type II and type III reactions.[8] IgG is also involved in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.[4]

物理的形状

0.01M PBS溶液 (pH 7.4, 1%BSA, 15mMアジ化ナトリウム含有)。

調製ノート

フルオレセインイソチオシアネ-トアイソマ-I(FITC)とのコンジュゲ-ションにより作製しています。この緑色色素は励起波長495および蛍光波長525 nmでの測定が効果的です。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)