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Merck

F3008

Sigma-Aldrich

抗マウスIgG (全分子)–FITC ヒツジ宿主抗体

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.46

由来生物

sheep

結合体

FITC conjugate

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

secondary antibodies

クローン

polyclonal

形状

buffered aqueous solution

テクニック

direct immunofluorescence: 1:32

保管温度

2-8°C

ターゲットの翻訳後修飾

unmodified

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詳細

Immunoglobulin G (IgG) is available in large quantities in the human serum. It constitutes about 10-20% of the plasma proteins. IgG is a glycoprotein, with 82-96% proteins and 4-18% carbohydrates. It consists of four sub-classes i.e IgG1, IgG2, IgG3, and IgG4. IgG is composed of four polypeptide chains-two heavy chains (γ chains) and two light chains (κ or λ chains) which are linked by inter-chain disulfide bonds.

アプリケーション

Anti-Mouse IgG (whole molecule)−FITC antibody produced in sheep has been used in:
  • flow cytometry
  • immunocytochemistry
  • immunofluorescent staining

生物化学的/生理学的作用

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections. The coupling of FITC to Anti- Mouse IgG (whole molecule) antibody allows for the visualization of protein by fluorescent microscopy.

その他情報

Antibody adsorbed with human serum proteins.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

F3008-1ML:
F3008-.5ML:
F3008PROC:
F3008-2ML:
F3008-VAR:
F3008-BULK:


試験成績書(COA)

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M A Zimmermann et al.
Haemophilia : the official journal of the World Federation of Hemophilia, 20(3), e215-e221 (2014-03-08)
About 10% of mutations in haemophilia A cases generate a premature termination codon in the factor VIII gene (F8). Upon therapeutic FVIII substitution, it was noted that the risk of developing inhibitors is higher when the nonsense mutation is located
Mariella D'Alessandro et al.
Journal of cell science, 115(Pt 22), 4341-4351 (2002-10-12)
The intermediate filament cytoskeleton is thought to confer physical resilience on tissue cells, on the basis of extrapolations from the phenotype of cell fragility that results from mutations in skin keratins. There is a need for functional cell assays in
Katsushi Suzuki et al.
PloS one, 15(8), e0236781-e0236781 (2020-08-11)
It has been reported that Bach1-deficient mice show reduced tissue injuries in diverse disease models due to increased expression of heme oxygenase-1 (HO-1)that possesses an antioxidant function. In contrast, we found that Bach1 deficiency in mice exacerbated skeletal muscle injury
Masaki Sato et al.
Cancer research, 80(6), 1279-1292 (2020-01-11)
Pancreatic ductal adenocarcinoma (PDAC) is among the cancers with the poorest prognoses due to its highly malignant features. BTB and CNC homology 1 (BACH1) has been implicated in RAS-driven tumor formation. We focused on the role of BACH1 in PDAC
Alan Renton et al.
Carcinogenesis, 24(7), 1177-1182 (2003-06-17)
The p53 tumour suppressor gene is a transcription factor that can induce cell cycle arrest and apoptosis. In response to various stress-inducing signals, p53 level increases and this is accompanied with increased activities of p53. Interestingly, the methylxanthine caffeine can

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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