D1260

デカメトニウムブロミド

crystalline

• 別名: デカメチレンビス(トリメチルアンモニウムブロミド), デカン-1,10-ビス(トリメチルアンモニウムブロミド)
• 化学式: (CH₃)₃N(Br)(CH₂)₁₀N(Br)(CH₃)₃
• CAS番号: 541-22-0
• 分子量: 418.29
• UNSPSC Code: 12352200
• NACRES: NA.77
• PubChem Substance ID: 24277833
• EC Number: 208-772-2
• Beilstein/REAXYS Number: 3728288
• MDL number: MFCD00011779
• Form: crystalline

特性

• form: crystalline
• Quality Segment: 200
• color: off-white
• mp: 263-267 °C (lit.)
• originator: GlaxoSmithKline
• SMILES string: [Br-].[Br-].C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C
• InChI: 1S/C16H38N2.2BrH/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;;/p-2
• InChI key: HLXQFVXURMXRPU-UHFFFAOYSA-L
• Gene Information: human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143), CHRND(1144), CHRNE(1145), CHRNG(1146)

詳細

Application

Decamethonium bromide has been used to induce paralysis in duck embryo.

Biochem/physiol Actions

ニコチン性アセチルコリンレセプタ-の部分アゴニストで神経筋遮断薬として作用し、横紋筋の脱分極を引き起こして活性をブロックします。

Decamethonium serves as a muscle relaxant and is also a neuromuscular blocking agent. It has a molecular weight of 258.4.[1]

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全性情報

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H315,H319,H335
• pcodes: P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• 保管分類: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges