A2780 Cell Line human

93112519, human ovary, Epithelial

• 別名: A-2780 Cells
• UNSPSCコード: 41106514

特性

• 製品名: A2780 Cell Line human, ovarian carcinoma, 93112519
• 由来生物: human ovary
• 成長モード: Adherent
• 核型: Not specified
• 形態: Epithelial
• 製品: Not specified
• 受容体: Not specified
• テクニック: cell culture | mammalian: suitable
• 関連疾患: cancer
• 輸送温度: dry ice
• 保管温度: −196°C

詳細

細胞株の由来

Human ovarian carcinoma

細胞株の説明

The A2780 human ovarian cancer cell line was established from tumour tissue from an untreated patient. Cells grow as a monolayer and in suspension in spinner cultures. A2780 is the parent line to the cisplatin resistant cell line A2780 cis (Sigma catalogue no. 93112517) and the adriamycin resistant cell line A2780 ADR (Sigma catalogue no. 93112520).

アプリケーション

A2780 cell line human is used in toxicity testing and cancer genetic studies.
A2780 cell line human has been used to:

• study the role of Snail and Slug in ovarian tumor neovascularization[1]
• overcome cisplatin resistance in ovarian cancer cells using liposome application[2]
• demonstrate the significance of NMDA (N-methyl-D-aspartate) receptors as targets for treatment of ovarian cancers[3]
• study the effect of low molecular weight heparin tinzaparin on cisplatin resistance in ovarian cancer cells[4]

DNAプロファイル

STR-PCR Data: Amelogenin: X
CSF1PO: 10,11
D13S317: 12,13
D16S539: 11,13
D5S818: 11,12
D7S820: 10
THO1: 6
TPOX: 8,10
vWA: 15,16

培地

RPMI-1640 + 2mM Glutamine + 10% Foetal Boving Serum (FBS).

継代と培養方法

Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 3-6x10,000cells/cm² using 0.05% Trypsin or Trypsin/EDTA; 5% CO₂; 37°C.

その他情報

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免責事項

This cell line has special release conditions: Commercial organisations are required to complete the ′Cell Line Release Authorisation for Research Use in Commercial Organisations′ release conditions form.