A8727

アンタラルミン 塩酸塩

≥98% (HPLC), solid, CRF1 antagonist

• 別名: N-ブチル-N-エチル-2,5,6-トリメチル-7-(2,4,6-トリメチルフェニル)-7H-ピロロール[2,3-d]ピリミジン-4-アミン 塩酸塩
• 実験式（ヒル表記法）: C₂₄H₃₄N₄·HCl
• CAS番号: 220953-69-5
• 分子量: 415.01
• MDL番号: MFCD05664721
• UNSPSCコード: 12352200
• PubChem Substance ID: 24724401
• NACRES: NA.77

特性

• product name: アンタラルミン 塩酸塩, ≥98% (HPLC), solid
• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: solid
• 保管条件: desiccated
• 色: off-white
• 溶解性: DMSO: >10 mg/mL
• 保管温度: 2-8°C
• SMILES記法: Cl[H].CCCCN(CC)c1nc(C)nc2n(c(C)c(C)c12)-c3c(C)cc(C)cc3C
• InChI: 1S/C24H34N4.ClH/c1-9-11-12-27(10-2)23-21-18(6)19(7)28(24(21)26-20(8)25-23)22-16(4)13-15(3)14-17(22)5;/h13-14H,9-12H2,1-8H3;1H
• InChI Key: CGDGXEDXEXACKQ-UHFFFAOYSA-N

詳細

アプリケーション

塩酸アンタラルミンはCRF1コルチコトロピン放出因子レセプターの非ペプチド性アンタゴニストです。

Antalarmin hydrochloride has been used:

• to study its effect on stress-induced tryptophan hydroxylase 2 activity
• to study the anxiogenic effects of corticotropin-releasing factor 1 (CRF1) activation
• to analyze the therapeutic effect of blocking corticotrophin-releasing hormone (CRH) signaling in treating social stress-induced depression

生物化学的／生理学的作用

Antalarmin serves as a non steroidal inhibitor of pregnancy even during the early stages. It is known to delay parturition. It also prevents the development of gastric ulcers which arises in response to stress.

塩酸アンタラルミンはCRF1コルチコトロピン放出因子レセプターの非ペプチド性アンタゴニストです。

特徴および利点

This compound is featured on the Corticotropin-Releasing Factor Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)