溶解性
0.1 M NaOH: 12 mg/mL
0.1 M HCl: 14 mg/mL
H2O: 5.2 mg/mL
methanol: insoluble
生物化学的／生理学的作用
Potent and selective NMDA receptor agonist
その他情報
Note: Under IUPAC nomenclature, this compound is designated as trans
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
dust mask type N95 (US), Eyeshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
A172-VAR:
A172-5MG:
A172-25MG:
A172-BULK:
最新バージョンのいずれかを選択してください：
R D Allan et al.
Journal of medicinal chemistry, 33(10), 2905-2915 (1990-10-01)
We report the synthesis of a series of 3-carboxy-, 3-(carboxymethyl)-, 3-(omega-phosphonoalkyl)-1-aminocyclobutane-1-carboxylic acids for evaluation as agonists or antagonists of neurotransmission at excitatory amino acid receptors, particularly N-methyl-D-aspartic acid (NMDA) receptors. The compounds were evaluated as agonists on their ability to
Barbara Banelli et al.
Cell cycle (Georgetown, Tex.), 14(21), 3418-3429 (2015-11-15)
Notwithstanding current multimodal treatment, including surgery, radiotherapy and chemotherapy with temozolomide (TMZ), median survival of glioblastoma (GBM) patients is about 14 months, due to the rapid emergence of cell clones resistant to treatment. Therefore, understanding the mechanisms underlying chemoresistance is
Yuri Chikano et al.
Molecular cancer therapeutics, 14(2), 564-574 (2014-12-17)
The failure of current treatment options for glioblastoma stems from their inability to control tumor cell proliferation and invasion. Biologically targeted therapies offer great hope and one promising target is glycogen synthase kinase-3β (GSK3β), implicated in various diseases, including cancer.
Xiujuan Shi et al.
Molecular medicine reports, 11(5), 3533-3538 (2015-01-13)
Spindle and kinetochore‑associated protein 1 (SKA1) is an important component of the human kinetochore, which plays a key role in mitosis. The resent study was designed to investigate the role of SKA1 in human glioblastoma. The results of the present
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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