85555

スペクチノマイシン 二塩酸塩 五水和物

≥98.0% (AT)

• 実験式（ヒル表記法）: C₁₄H₂₄N₂O₇ · 2HCl · 5H₂O
• CAS番号: 22189-32-8
• 分子量: 495.35
• Beilstein: 5684150
• EC Number: 244-554-3
• MDL番号: MFCD00150886
• UNSPSCコード: 51101500
• PubChem Substance ID: 57653052

特性

• 由来生物: synthetic
• アッセイ: ≥98.0% (AT)
• 形状: solid
• 色: white
• 溶解性: H₂O: 50 mg/mL, clear, faintly yellow
• 抗生物質活性スペクトル: Gram-negative bacteria; Gram-positive bacteria
• 作用機序: protein synthesis | interferes
• 保管温度: 2-8°C
• SMILES記法: Cl[H].Cl[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H][C@@]12O[C@H](C)CC(=O)[C@]1(O)O[C@]3([H])[C@@H](NC)[C@@H](O)[C@@H](NC)[C@H](O)[C@@]3([H])O2
• InChI: 1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1
• InChI Key: DCHJOVNPPSBWHK-UXXUFHFZSA-N

詳細

詳細

Chemical structure: aminoglycoside

アプリケーション

Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.

注意

Solutions can be stored at 2-8°C for several weeks or at -20°C for more extended periods.

調製ノート

Stock solutions should be prepared at 10 mg/mL in water and filter sterilized.

その他情報

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)