73156

N-Methyl-L-serine

≥98% (TLC)

• 別名: (S)-3-Hydroxy-2-(methylamino)propionic acid, N-Me-Ser-OH
• 実験式（ヒル表記法）: C₄H₉NO₃
• CAS番号: 2480-26-4
• 分子量: 119.12
• Beilstein: 2498641
• MDL番号: MFCD00037756
• UNSPSCコード: 12352202
• PubChem Substance ID: 329764666
• NACRES: NA.32

特性

• アッセイ: ≥98% (TLC)
• フォーム: powder
• 光学活性: [α]/D +9.5±1.0°, c = 1 in 1 M HCl
• 組成: carbon, 39.5-41.1% ; nitrogen, 11.5-12.0%
• 色: white
• mp: 204 °C
• SMILES記法: CN[C@@H](CO)C(O)=O
• InChI: 1S/C4H9NO3/c1-5-3(2-6)4(7)8/h3,5-6H,2H2,1H3,(H,7,8)/t3-/m0/s1
• InChI Key: PSFABYLDRXJYID-VKHMYHEASA-N

詳細

生物化学的／生理学的作用

N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease[1], neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue. N-Methyl-L-serine stimulates hyaluronan production in human skin fibroblasts[2].

N-Methyl-L-serine has been found to stimulate production of high molecular mass hyaluronan in human fibroblasts. This effect was specific to methylated L-serine and not observed with other methylated amino acids. [2]

包装

底の開いたガラス瓶内容物は内部に挿入され接着された円錐部に入っています。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable