171R-1

CD71 (EP232) Rabbit Monoclonal Primary Antibody

• 別名: TFR1, TRF, TRFR, Transferrin Receptor 1, p90, transferrin receptor (p90, CD71)
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100; 500
• 結合体: unconjugated
• 抗体製品の状態: culture supernatant
• 抗体製品タイプ: primary antibodies
• クローン: EP232, monoclonal
• 詳細: For In Vitro Diagnostic Use in Select Regions (See Chart)
• 形状: buffered aqueous solution
• 化学種の反応性: human
• 包装: vial of 0.1 mL concentrate (171R-14); vial of 0.1 mL concentrate Research Use Only (171R-14-RUO); vial of 0.5 mL concentrate (171R-15); vial of 1.0 mL concentrate (171R-16); vial of 1.0 mL concentrate Research Use Only (171R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (171R-17-RUO); vial of 1.0 mL predilute ready-to-use (171R-17); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (171R-18-RUO); vial of 7.0 mL predilute ready-to-use (171R-18)
• メーカー／製品名: Cell Marque^™
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)
• アイソタイプ: IgG
• コントロール: bone marrow
• 輸送温度: wet ice
• 保管温度: 2-8°C
• 視覚化: cytoplasmic, membranous

詳細

詳細

Transferrin receptor 1 (CD71) is expressed on placental syncytiotrophoblasts, myocytes, basal keratinocytes, hepatocytes, endocrine pancreas, spermatocytes, and erythroid precursors. The level of transferrin receptor expression is highest in early erythroid precursors through the intermediate normoblast phase, after which expression decreases through the reticulocyte phase. The maturation of erythrocytes results in loss of transferrin receptor expression. AntiCD71 is useful in identifying erythroid precursors. The high level of transferrin receptor within erythroid precursors makes anti-CD71 an excellent marker for evaluation of erythroid precursors within bone marrow biopsy specimens and shows the following features: 1) distinct membranous and cytoplasmic staining pattern, which is easily recognized in bone marrow biopsy; 2) restriction to erythroid lineage within bone marrow biopsy specimens; 3) CD71 expression decreases with the maturation of erythrocytes, with the highest level seen in early forms and the lowest level in late normoblast stage, and most importantly; 4) mature erythrocytes do not express CD71.

品質

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

関連事項

CD71 Positive Control Slides, Product No. 171S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

物理的形状

Predilute: diluted in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Concentrate: diluted in Phosphate Buffered Saline, pH 7.2, with 1% BSA and <0.1% Sodium Azide

調製ノート

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その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable