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Merck

95197

Supelco

コウジ酸

analytical standard

別名:

2-ヒドロキシメチル-5-ヒドロキシ-γ-ピロン, 5-ヒドロキシ-2-(ヒドロキシメチル)-4H-ピラン-4-オン

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About This Item

実験式(ヒル表記法):
C6H6O4
CAS番号:
分子量:
142.11
Beilstein:
120895
EC Number:
MDL番号:
UNSPSCコード:
85151701
PubChem Substance ID:
NACRES:
NA.24

グレード

analytical standard

品質水準

アッセイ

≥99.0% (HPLC)

シェルフライフ

limited shelf life, expiry date on the label

テクニック

HPLC: suitable
gas chromatography (GC): suitable

mp

152-155 °C (lit.)

アプリケーション

cleaning products
cosmetics
food and beverages
personal care

フォーマット

neat

SMILES記法

OCC1=CC(=O)C(O)=CO1

InChI

1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2

InChI Key

BEJNERDRQOWKJM-UHFFFAOYSA-N

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関連するカテゴリー

詳細

Kojic acid, a tyrosinase inhibitor, is produced by several fungi species, including Aspergillus oryzae. It exhibits skin-lightening property, due to its ability to chelate the copper-containing enzyme tyrosinase in the formation of melanin. Kojic acid is also commonly used as a whitening agent in regular cosmetics, bleaching cosmetics, etc. It is found to be a therapeutic agent and helps in preventing pigmentation.

アプリケーション

Kojic acid may be used as an analytical reference standard for the determination of the analyte in skin whitening cosmetics and bleaching cosmetics using high performance liquid chromatography with UV detection (HPLC-UV).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生物化学的/生理学的作用

チロシナ-ゼ阻害剤です。

おすすめ製品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

保管分類コード

11 - Combustible Solids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

95197-VAR:
95197-100MG:
95197-BULK:


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試験成績書(COA)

Lot/Batch Number

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Simultaneous determination of magnesium ascorbyl phosphate, ascorbyl glucoside, kojic acid, arbutin and hydroquinone in skin whitening cosmetics by HPLC
Huang C-S, et al.
Journal of food and drug analysis, 12(1) (2004)
Quantitative determination of $\alpha$-arbutin, $\beta$-arbutin, kojic acid, nicotinamide, hydroquinone, resorcinol, 4-methoxyphenol, 4-ethoxyphenol, and ascorbic acid from skin whitening products by HPLC-UV
Wang YH, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 98(1), 5-12 (2015)
Atsushi Yoshimori et al.
Bioorganic & medicinal chemistry, 22(21), 6193-6200 (2014-10-08)
Tyrosinase inhibitors have become increasingly critical agents in cosmetic, agricultural, and medicinal products. Although a large number of tyrosinase inhibitors have been reported, almost all the inhibitors were unfortunately evaluated by using commercial available mushroom tyrosinase. Here, we examined the
Combining high-performance liquid chromatography with on-line microdialysis sampling for the simultaneous determination of ascorbyl glucoside, kojic acid, and niacinamide in bleaching cosmetics.
Lin CH et al
Analytica Chimica Acta, 581(1), 102-107 (2007)
Safak Ozhan Kocakaya et al.
Iranian journal of pharmaceutical research : IJPR, 19(2), 187-198 (2020-11-24)
Recently Nutrition and Food Chemistry researches have been focused on plants and their products or their secondary metabolites having anti-alzheimer, anti-cancer, anti-aging, and antioxidant properties. Among these plants Salvia L. (Lamiaceae) species come into prominence with their booster effects due

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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