94348

N-(3-Phenylpropionyl)glycine

analytical standard

• 別名: 2-[(3-Phenylpropionyl)amino]acetic acid, 3-Phenylpropionyl glycine, N-(1-Oxo-3-phenylpropyl)glycine, N-(3-Phenylpropanoyl)glycine
• 実験式（ヒル表記法）: C₁₁H₁₃NO₃
• CAS番号: 56613-60-6
• 分子量: 207.23
• Beilstein: 2976435
• MDL番号: MFCD03011415
• UNSPSCコード: 12352209
• PubChem Substance ID: 329770329

特性

• グレード: analytical standard
• 品質水準: 100
• アッセイ: ≥98.0% (HPLC)
• シェルフライフ: limited shelf life, expiry date on the label
• アプリケーション: clinical testing
• フォーマット: neat
• 保管温度: 2-8°C
• InChI: 1S/C11H13NO3/c13-10(12-8-11(14)15)7-6-9-4-2-1-3-5-9/h1-5H,6-8H2,(H,12,13)(H,14,15)
• InChI Key: YEIQSAXUPKPPBN-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

Phenylpropionylglycine is an acylglycine. Acylglycines are normally minor metabolites of fatty acids. However, the excretion of certain acylglycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine ↔ CoA + N-acylglycine. The detection of phenylpropionylglycine in urine after an oral load of phenylpropionic acid can be used to diagnose deficiency of medium-chain acyl-CoA dehydrogenase, a frequent and treatable metabolic defect.

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安全性情報

• ピクトグラム: GHS05
• シグナルワード: Danger
• 危険有害性情報: H318
• 注意書き: P280 - P305 + P351 + P338
• 危険有害性の分類: Eye Dam. 1
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable