90240

グリセリルトリアセタート

≥99.0% (GC)

• 別名: 1,2,3-トリアセチルグリセリン, 1,2,3-トリアセトキシプロパン, グリセリントリアセタート, トリアセチン
• 化学式: (CH₃COOCH₂)₂CHOCOCH₃
• CAS番号: 102-76-1
• 分子量: 218.20
• Beilstein: 1792353
• EC Number: 203-051-9
• MDL番号: MFCD00008716
• UNSPSCコード: 12352211
• PubChem Substance ID: 329769862
• NACRES: NA.25

特性

• 品質水準: 200
• アッセイ: ≥99.0% (GC)
• 形状: liquid
• 屈折率: n20/D 1.431
• bp: 258-260 °C (lit.)
• 密度: 1.158 g/mL at 20 °C
• 脂質タイプ: saturated FAs
• SMILES記法: CC(=O)OCC(COC(C)=O)OC(C)=O
• InChI: 1S/C9H14O6/c1-6(10)13-4-9(15-8(3)12)5-14-7(2)11/h9H,4-5H2,1-3H3
• InChI Key: URAYPUMNDPQOKB-UHFFFAOYSA-N

詳細

アプリケーション

• Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state.: This groundbreaking study utilizes glyceryl triacetate as part of an epigenetic priming strategy to sensitize pancreatic ductal adenocarcinoma to Vitamin D, marking a significant advancement in cancer treatment modalities (He et al., 2024).


• Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice.: Research demonstrates glyceryl triacetate′s effectiveness in enhancing blood-brain barrier repair post-ischemic stroke via lipogenesis pathways, offering insights into novel stroke recovery treatments (Wei et al., 2023).


• Development of A Nanostructured Lipid Carrier-Based Drug Delivery Strategy for Apigenin: Experimental Design Based on CCD-RSM and Evaluation against NSCLC In Vitro.: This study details the formulation of a nanostructured lipid carrier incorporating glyceryl triacetate, optimized for delivering apigenin to combat non-small cell lung cancer, emphasizing the potential of glyceryl triacetate in targeted therapy applications (Wang et al., 2023).


• Are New Phthalate Ester Substitutes Safer than Traditional DBP and DiBP Comparative Endocrine-Disrupting Analyses on Zebrafish Using In Vivo, Transcriptome, and In Silico Approaches.: Investigating glyceryl triacetate as a safer alternative to traditional phthalate esters, this study explores its lower endocrine-disrupting effects, contributing to safer industrial and pharmaceutical applications (Tan et al., 2023).


• Glyceryl triacetate feeding in mice increases plasma acetate levels but has no anticonvulsant effects in acute electrical seizure models.: This research evaluates the biochemical impact of glyceryl triacetate on plasma acetate levels, providing valuable data on its metabolic effects despite a lack of anticonvulsant properties in specific seizure models (Xu et al., 2022).

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): 298.4 °F - closed cup
• 引火点(℃): 148 °C - closed cup
• 個人用保護具 (PPE): Eyeshields, Gloves