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Merck

41131

Supelco

Mettler-Toledo®較正物質ME 51143091、サッカリン

traceable to primary standards (LGC)

別名:

サッカリン, 2,3-ジヒドロキシ-1,2-ベンゾイソチアゾール-3-オン-1,1-ジオキシド, 2-スルホ安息香酸イミド, o-安息香酸スルフィミド

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About This Item

実験式(ヒル表記法):
C7H5NO3S
CAS番号:
分子量:
183.18
Beilstein:
6888
EC Number:
MDL番号:
UNSPSCコード:
20121904
PubChem Substance ID:
NACRES:
NA.24

グレード

analytical standard

品質水準

品質

traceable to primary standards (LGC)

シェルフライフ

limited shelf life, expiry date on the label

mp

226-229 °C (lit.)

アプリケーション

food and beverages
pharmaceutical

フォーマット

neat

SMILES記法

O=C1NS(=O)(=O)c2ccccc12

InChI

1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)

InChI Key

CVHZOJJKTDOEJC-UHFFFAOYSA-N

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詳細

Mettler-Toledo calibration substance ME 51143091, saccharin is an analytical standard, designed for the routine calibration of Mettler-Toledo melting point instrument. Its value is an average of 6 to 12 measurements with a Mettler-Toledo MP90 Excellence instrument that is calibrated against primary standards. The melting point is validated by Capillary method as per European Pharmacopeia (2.2.14.)

アプリケーション

Saccharin Mettler-Toledo calibration substance ME 51143091 is a melting point calibration standard used to calibrate Mettler-Toledo mp instruments.

生物化学的/生理学的作用

哺乳類の甘味物質です。ショウジョウバエにおいて、グルコース特異的なグリセロール味覚受容体結合部位の存在が提唱されています。

特徴および利点

  • Traceable to a primary standard from LGC, London
  • Melting point evaluation conducted in both thermodynamic and pharmacopeia modes for physically correct and heating rate dependent melting point determinations, respectively
  • Available with certificates of analysis and safety data sheet
  • A product of analytical standard grade to help meet the QC/QA requirements of melting point determination
  • Uncertainty of measurement up to ± 0.3 °C

法的情報

Mettler-Toledo is a registered trademark of Mettler-Toledo, Inc.

保管分類コード

11 - Combustible Solids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, type N95 (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

41131-BULK:
41131-VAR:
41131-5G:


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Steven Zukerman et al.
Physiology & behavior, 109, 33-41 (2012-12-04)
In a recent study, intragastric (IG) self-infusion of 16% glucose stimulated 1-h intake and conditioned a preference for a flavored saccharin solution in C57BL/6J mice (Zukerman et al., 2011). Experiment 1 of the present study presents a concentration-response analysis of
Jennifer E Nyland et al.
Behavioural brain research, 240, 87-90 (2012-11-24)
Addiction is a chronic disease where periods of abstinence are riddled with instances of craving, withdrawal, and eventual relapse to escalated drug use. Cues previously associated with drug use can have a deleterious effect on this cycle by precipitating withdrawal
Hellmuth Lilienthal et al.
Toxicology, 311(1-2), 52-60 (2013-02-14)
Many chemicals are known to exhibit endocrine activity and affect reproductive functions in vertebrates and invertebrates. Endocrine effects include influences on sexual differentiation of the brain during development and reproductive and non-reproductive behavior in adult offspring. We previously demonstrated that
Amjad Alhalaweh et al.
Molecular pharmaceutics, 9(9), 2605-2612 (2012-08-08)
Cocrystals constitute an important class of pharmaceutical solids for their remarkable ability to modulate solubility and pH dependence of water insoluble drugs. Here we show how cocrystals of indomethacin-saccharin (IND-SAC) and carbamazepine-saccharin (CBZ-SAC) enhance solubility and impart a pH-sensitivity different
Hugh P Morgan et al.
The Biochemical journal, 448(1), 67-72 (2012-08-22)
PYK (pyruvate kinase) plays a central role in the metabolism of many organisms and cell types, but the elucidation of the details of its function in a systems biology context has been hampered by the lack of specific high-affinity small-molecule

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