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Merck

RPTMAG-86K

Millipore

MILLIPLEX® Rat Pituitary Magnetic Bead Panel - Endocrine Multiplex Assay

The analytes available for this multiplex kit are: ACTH, BDNF, FSH, GH, LH, Prolactin, TSH.

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About This Item

UNSPSCコード:
12161503
eCl@ss:
32161000
NACRES:
NA.84

To order a Milliplex® kit, please search for your analyte of interest.

品質水準

交差性

rat

メーカー/製品名

Milliplex®

assay range

accuracy: 75%
(GH)

accuracy: 88%
(ACTH)

accuracy: 89%
(LH)

accuracy: 90%
(TSH)

sensitivity: 0.38 pg/mL
(BDNF)

sensitivity: 0.87 pg/mL
(TSH)

sensitivity: 1.95 pg/mL
(ACTH)

sensitivity: 3.28 pg/mL
(LH)

sensitivity: 4.64 pg/mL
(Prolactin)

sensitivity: 6.50 pg/mL
(GH)

sensitivity: 7.62 pg/mL
(FSH)

standard curve range: 16-50,000 pg/mL
(GH, Prolactin)

standard curve range: 3.2-10,000 pg/mL
(ACTH, BDNF, LH, TSH)

standard curve range: 32-100,000 pg/mL
(FSH)

inter-assay cv: <20%
intra-assay cv: <10%

テクニック

multiplexing: suitable

検出方法

fluorometric (Luminex xMAP)

輸送温度

wet ice

詳細

Called the “master gland” because it controls many other endocrine glands, the pituitary secretes several key hormones that play important roles in the regulation of metabolism, growth, and reproduction. Piuitary hormones are responsible for the stimulation of the adrenal gland (ACTH), thyroid gland (TSH), ovaries and testes (FSH, LH) and breast milk production (prolactin), as well as blood pressure and the amount of water excreted by the kidneys. Through its connection with the pituitary, the hypothalamus modulates endocrine function by detecting hormone levels. Brain-Derived Neurotrophic Factor (BDNF) is a member of NGF family of neurotrophic factors which are required for differentiation and survival of specific neuronal sub-populations.

MILLIPLEX® Rat Pituitary Panel is a 7-plex kit to be used for the simultaneous quantification of any or all of the following analytes in rat serum or plasma samples, rat tissue extract, or cell/tissue culture supernatant samples: Growth Hormone (GH), Thyroid-Stimulating Hormone (TSH), Adrenocorticotropic Hormone (ACTH), Luteinizing Hormone (LH), Prolactin, Follicle-Stimulating Hormone (FSH), and Brain-Derived Neurotrophic Factor (BDNF). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Endocrine

アプリケーション

  • Analytes: Adrenocorticotropic Hormone (ACTH), Brain-Derived Neurotrophic Factor (BDNF), Follicle-Stimulating Hormone (FSH), Growth Hormone (GH), Luteinizing Hormone (LH), Prolactin, Thyroid-Stimulating Hormone (TSH)
  • Recommended Sample Type: Rat serum, plasma, cell/tissue culture supernatants or lysates
  • Recommended Sample Dilution: 25 μL per well 1:3 diluted serum or plasma; cell/tissue culture samples may require dilution in an appropriate control medium.
  • Assay Run Time: Overnight (16-18 hours) at 2-8°C
  • Research Category: Endocrine
  • Research Subcategory: Metabolism

特徴および利点

Design your multiplex kit by choosing available analytes within this panel.

法的情報

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

ピクトグラム

Skull and crossbonesEnvironment

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

保管分類コード

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

毒物及び劇物取締法

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PRTR

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消防法

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労働安全衛生法名称等を表示すべき危険物及び有害物

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労働安全衛生法名称等を通知すべき危険物及び有害物

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カルタヘナ法

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Jan Code

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試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Vivi F H Jensen et al.
Scientific reports, 10(1), 5609-5609 (2020-03-30)
Maternal hypoglycaemia throughout gestation until gestation day (GD)20 delays foetal growth and skeletal development. While partially prevented by return to normoglycaemia after completed organogenesis (GD17), underlying mechanisms are not fully understood. Here, we investigated the pathogenesis of these changes and
Global but not gonadotrope-specific disruption of Bmal1 abolishes the luteinizing hormone surge without affecting ovulation.
Chu, A; Zhu, L; Blum, ID; Mai, O; Leliavski, A; Fahrenkrug, J; Oster, H; Boehm, U; Storch, KF
Endocrinology null
Jennifer M Rojas et al.
Toxicologic pathology, 46(7), 777-798 (2018-10-23)
The obese rodent serves as an indispensable tool for proof-of-concept efficacy and mode-of-action pharmacology studies. Yet the utility of this disease model as an adjunct to the conventional healthy animal in the nonclinical safety evaluation of anti-obesity pharmacotherapies has not
Mirjam Kowallick et al.
Frontiers in pediatrics, 9, 723928-723928 (2021-11-23)
Introduction: High oxygen concentrations have been identified as one factor contributing to the pathogenesis of the retinopathia of prematurity, chronic lung disease of the preterm infant and preterm brain injury. Preterm infants also show short- and long-term alterations of the
Renee N Sadowski et al.
Neurotoxicology and teratology, 42, 17-24 (2014-01-21)
Previous work has shown that exposure to bisphenol A (BPA) can affect anxiety behavior. However, no studies have examined whether administration of this endocrine disruptor during the perinatal period has the potential to induce alterations in cognitive behavior in both

関連コンテンツ

Multiplex toxicity assays enable researchers to simultaneously measure multiple toxicity biomarkers of various organs to gain a better understanding of toxicity. Explore how MILLIPLEX® multiplex toxicity assays are advancing research on liver injury, kidney toxicity, genotoxicity, and more.

マルチプレックス毒性アッセイにより、さまざまな臓器の複数の毒性バイオマーカーを同時に測定することで、毒性の理解を深めることができます。MILLIPLEX®マルチプレックス毒性アッセイが、肝障害、腎毒性、遺伝毒性などに関する研究をどのように進展させるかについてご覧ください。

Multiplex immunoassays, such as MILLIPLEX® multiplex metabolic assays, are critical in metabolic syndrome research because they provide a full picture of the different conditions related to it, like diabetes and obesity, as well as save time and sample volume.

MILLIPLEX®マルチプレックス代謝アッセイなどのマルチプレックス・イムノアッセイは、メタボリックシンドローム研究に重要です。糖尿病や肥満など、関連するさまざまな病態の全体像を把握でき、時間とサンプル量を節約できるためです。

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アクティブなフィルタ

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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