ウェスタンブロッティング:希釈倍率1:1,000で使用、10 µgのヒト脳組織ライセートにおいてExo70を検出できます。 免疫細胞染色: 独立したラボが代表的なロットをExo70細胞で使用しました。(Hsu, S.C., et al. (2001).The Journal of Neuroscience.21(11):3839–3848.) 免疫組織染色: 独立したラボが前回のロットをIFで使用しました。(Hsu, S.C., et al. (2011).The Journal of Neuroscience.31(10):3522–3535.)
Hormone secretion from metabolically active tissues, such as pancreatic islets, is governed by specific and highly regulated signaling pathways. Defects in insulin secretion are among the major causes of diabetes. The molecular mechanisms underlying regulated insulin secretion are, however, not
Cellular and molecular life sciences : CMLS, 79(1), 61-61 (2022-01-10)
Apical localization of Intercellular Adhesion Receptor (ICAM)-1 regulates the adhesion and guidance of leukocytes across polarized epithelial barriers. Here, we investigate the molecular mechanisms that determine ICAM-1 localization into apical membrane domains of polarized hepatic epithelial cells, and their effect
Epithelial intercellular adhesion molecule (ICAM)-1 is apically polarized, interacts with, and guides leukocytes across epithelial barriers. Polarized hepatic epithelia organize their apical membrane domain into bile canaliculi and ducts, which are not accessible to circulating immune cells but that nevertheless