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詳細
APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. APRIL, along with another TNF family member, BAFF, compete for two receptors, TACI and BCMA. ARPIL has the ability to stimulate proliferation of various tumor cell lines including Jurkat T cells and MCF-7 carcinoma cells. Like BAFF, APRIL also stimulates the proliferation of B and T cells. The human APRIL gene codes for at least four alternatively spliced transcriptional variants, which give rise to different isoforms of the APRIL precursor protein. All isoforms can be cleaved by the protease, furin, to release a soluble C-terminal fragment, which comprises the TNF like receptor binding of the APRIL precursor.
Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues.
Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues.
Product Source: Protein is expressed in E.coli.
アプリケーション
Research Category
幹細胞研究
幹細胞研究
Research Sub Category
成長因子及び受容体
成長因子及び受容体
品質
Measured by its ability to induce cell death in Jurkat cells.
物理的形状
Product is presented in 10 mM Sodium Phosphate, pH 7.5 + 500 mM NaCl + 5% Trehalose and is filtered through a 0.2 micron filter before lyophilization.
保管および安定性
Store at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
保管分類コード
13 - Non Combustible Solids
WGK
WGK 1
適用法令
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Jan Code
GF177:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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