FCMAB250A4

Milli-Mark^® Anti-Bcl-2 Antibody, Alexa Fluor^™488, clone AW604

clone AW604, Milli-Mark^®, from mouse

• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: ALEXA FLUOR^™ 488
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: AW604, monoclonal
• 化学種の反応性: human
• メーカー／製品名: Milli-Mark^®
• テクニック: flow cytometry: suitable
• アイソタイプ: IgG2a
• NCBIアクセッション番号: NP_000624
• UniProtアクセッション番号: P10415
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... BCL2(596)

詳細

詳細

Bcl-2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Bcl-2 also regulates cell death by controlling the mitochondrial membrane permeability and appears to function in a feedback loop system with caspases. It appears to Inhibit caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Further understanding in how Bcl-2 functions and interacts with other proteins to promote or inhibit apoptosis may lead to new treatments for cancer, neurological disorders and autoimmune diseases.

特異性

Antibody recognizes Bcl-2.

免疫原

KLH-conjugated, synthetic peptide corresponding to human Bcl-2

アプリケーション

Research Category
アポトーシス及び癌

Research Sub Category
BCL2とその阻害

This Milli-Mark Bcl-2 antibody is validated for use in Flow for the detection of the Milli-Mark Bcl-2 protein.

品質

Evaulated by flow cytometery using Jurkat cells.

ターゲットの説明

26 kDa Calculated

物理的形状

Protein G Purified

Purified mouse monoclonal IgG2a conjugated to Alexa Fluor^™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

保管および安定性

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

アナリシスノート

Control
Jurkat Cells

法的情報

ALEXA FLUOR is a trademark of Life Technologies

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Alexa Fluor^™ is a registered trademark of Molecular Probes, Inc.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable