AB5930

Anti-Potassium Channel ERG1 Antibody, CT

Chemicon^®, from rabbit

• 別名: Ether-a-go-go-related Gene Product, HERG1, MERG1, RERG1
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human, mouse, rat
• メーカー／製品名: Chemicon^®
• テクニック: immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• NCBIアクセッション番号: NM_000238.2; NM_172056.1; NM_172057.1
• UniProtアクセッション番号: Q12809
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... KCNH2(3757)

詳細

詳細

ERG1 encodes the pore forming alpha subunit of the voltage-gated channels that conduct the rapid delayed rectifier potassium current, which leads to termination of the cardiac ventricular action potential. A large number of commercially available therapeutic agents (antiarrhythmics, antihistamines, antibiotics and antidepressants) have been shown to preferentially block ERG1 and cause a disorder of cardiac action potential depolarization that predisposes affected individuals to ventricular arrhythmia and sudden death.

特異性

ERG1 protein. By western blot, antibody recognizes bands at 175 and 205 kDa (glycosylated) or 135 and 165 kDa (deglycosylated).

免疫原

Epitope: C-terminus

Synthetic peptide corresponding to the C-terminus of ERG1 (aa 1145-1159 of HERG1).

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
イオンチャネル及びトランスポーター

Anti-Potassium Channel ERG1 Antibody, C-terminus detects level of Potassium Channel ERG1 & has been published & validated for use in IC, IH, IP & WB.

Immunoblotting: 5 μg/mL

Immunocytochemistry

Immunohistochemistry on 4% paraformaldehyde fixed tissues.

Immunoprecipitation

Optimal working dilutions must be determined by end user.

物理的形状

Liquid in PBS with 0.1% sodium azide.

保管および安定性

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles

アナリシスノート

Control
Positive control tissue: Heart

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法的情報

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable