おすすめの製品
由来生物
rabbit
品質水準
抗体製品の状態
serum
抗体製品タイプ
primary antibodies
クローン
polyclonal
化学種の反応性
mouse
メーカー／製品名
Chemicon®
テクニック
ELISA: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
neutralization: suitable
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
dry ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
mouse ... Ifnb1(15977)
特異性
Reacts with mouse Interferon beta (IFNbeta). No reactivity is seen with IFNalpha or gamma
免疫原
Mouse IgG, whole molecule.
アプリケーション
Research Category
炎症及び免疫
炎症及び免疫
Research Sub Category
サイトカイン及びサイトカイン受容体
サイトカイン及びサイトカイン受容体
Cytopathic effect inhibition assay: 2 x 10E5 neutralization units per mL of antiserum. One neutralization unit is the amount of antiserum required to neutralize 1 unit of mouse IFN-beta. This material is prepared specifically for effective neutralization of mouse IFN-beta.
Western blot (1:500) The antibody reacts with a 19kDa band coresponding to Mu-IFN-beta. Protocol below:
1. Put protein (approx 50ng) in blocking solution for 30-60 min RT
2. Add Primary antibody (1:500) to blocking solution
3. Agitate membrane for 60 min, RT
4. Wash 3X for 5min each with PBS-Tween
5. Add secondary antibody (1:1000) after diluting in PBS-Tween
6. Gentle agitation for 60min.
7. Wash 3X for 5min each with PBS-Tween
8. Develop with reaction kit of choice
Immunoprecipitation
Immunohistochemistry
ELISA
Optimal working dilutions must be determined by end user.
Western blot (1:500) The antibody reacts with a 19kDa band coresponding to Mu-IFN-beta. Protocol below:
1. Put protein (approx 50ng) in blocking solution for 30-60 min RT
2. Add Primary antibody (1:500) to blocking solution
3. Agitate membrane for 60 min, RT
4. Wash 3X for 5min each with PBS-Tween
5. Add secondary antibody (1:1000) after diluting in PBS-Tween
6. Gentle agitation for 60min.
7. Wash 3X for 5min each with PBS-Tween
8. Develop with reaction kit of choice
Immunoprecipitation
Immunohistochemistry
ELISA
Optimal working dilutions must be determined by end user.
Detect Interferon-β using this Anti-Interferon-β Antibody validated for use in ELISA, IP, WB, IH, NEUT.
包装
2x10(e4) units
物理的形状
Rabbit polyclonal serum in buffer containing 0.3 M NaHCO3 and 200 mM NaCl.
保管および安定性
Maintain frozen at -20°C or below for retention of full activity, for up to 12 months. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum.
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our 製品選択ツール.
保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
AB2215:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Choon Kit Tang et al.
PloS one, 8(3), e60038-e60038 (2013-04-05)
5,6-Dimethylxanthenone-4-acetic acid (DMXAA), a potent type I interferon (IFN) inducer, was evaluated as a chemotherapeutic agent in mouse cancer models and proved to be well tolerated in human cancer clinical trials. Despite its multiple biological functions, DMXAA has not been
Anna Niewiadomska-Cimicka et al.
International journal of molecular sciences, 25(8) (2024-04-27)
Polyglutamine (polyQ)-encoding CAG repeat expansions represent a common disease-causing mutation responsible for several dominant spinocerebellar ataxias (SCAs). PolyQ-expanded SCA proteins are toxic for cerebellar neurons, with Purkinje cells (PCs) being the most vulnerable. RNA interference (RNAi) reagents targeting transcripts with
Dwijit GuhaSarkar et al.
Molecular oncology, 11(2), 180-193 (2017-01-18)
The highly invasive property of glioblastoma (GBM) cells and genetic heterogeneity are largely responsible for tumor recurrence after the current standard-of-care treatment and thus a direct cause of death. Previously, we have shown that intracranial interferon-beta (IFN-β) gene therapy by
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）