8.51021

N₃-(PEG)₇-COOH (33 atoms)

Novabiochem^®

• 別名: N₃-(PEG)₇-COOH (33 atoms), O-(2-Azidoethyl)-O′-(N-diglycolyl-2-aminoethyl)-heptaethyleneglycol
• 実験式（ヒル表記法）: C₂₂H₄₂N₄O₁₂
• CAS番号: 846549-37-9
• 分子量: 554.59
• MDL番号: MFCD10001327
• UNSPSCコード: 12352106
• NACRES: NA.22

特性

• 品質水準: 400
• 製品種目: Novabiochem^®
• アッセイ: ≥97.0% (HPLC)
• フォーム: oil
• 反応適合性: reaction type: click chemistry
• メーカー／製品名: Novabiochem^®
• アプリケーション: peptide synthesis
• 保管温度: 2-8°C
• SMILES記法: [N+](=[N-])=NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)COCC(=O)O
• InChI: 1S/C22H42N4O12/c23-26-25-2-4-31-6-8-33-10-12-35-14-16-37-18-17-36-15-13-34-11-9-32-7-5-30-3-1-24-21(27)19-38-20-22(28)29/h1-20H2,(H,24,27)(H,28,29)
• InChI Key: WWDNBBVPYDZICO-UHFFFAOYSA-N

詳細

詳細

This building block is prepared from highly purified PEG to ensure homogeneous products free from contaminating PEG oligomers. In this derivative the azido group acts as an orthogonally masked amine; it is stable to both TFA and piperidine but is easily converted to an amine by treatment with phosphines or thiols. For a similar spacer, see reference ^[1]. This material is now only available as an oil.

Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS

Literature references
^[1] J. Mack, et al. (1999) J. Peptide Sci., 6, 135.

関連事項

Replaces: 01-63-0103

アナリシスノート

Color (visual): slight yellow to yellow
Appearance of substance (visual): oil
Assay (HPLC, area%): ≥ 97.0 % (a/a)

法的情報

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315 - H319 - H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable