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由来生物
rabbit
品質水準
抗体製品の状態
purified antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
liquid
含まれません
preservative
化学種の反応性
human, rat, mouse
メーカー/製品名
Calbiochem®
保管条件
OK to freeze
avoid repeated freeze/thaw cycles
アイソタイプ
IgG
輸送温度
wet ice
保管温度
−70°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... UCP1(7350)
詳細
Protein A purified rabbit polyclonal antibody. Recognizes the UCP-1 protein.
Recognizes the UCP-1 protein.
This Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb is validated for use in Immunoblotting for the detection of Uncoupling Protein-1 (UCP-1) (145-159).
免疫原
Mouse
a synthetic peptide [(C)SHLHGIKPRYTGTYN] corresponding to amino acids 145-159 of mouse UCP1
アプリケーション
Immunoblotting (1:1000)
警告
Toxicity: Standard Handling (A)
物理的形状
In PBS.
再構成
Following initial thaw, aliquot and freeze (-70°C).
その他情報
Does not exhibit cross-reactivity with UCP2 or UCP3. Since this antigen sequence is highly conserved, cross-reactivity across a broad range of species is expected. Variables associated with assay conditions will dictate the proper working dilution.
Kozak, L.P., et al. 1988. J. Biol. Chem. 263, 12274.
法的情報
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
662045-100UL:
662045-UL:
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(4), 1151-1159 (2009-11-18)
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PloS one, 2(8), e683-e683 (2007-08-02)
Growing evidences indicate that proteases are implicated in adipogenesis and in the onset of obesity. We previously reported that the cysteine protease cathepsin K (ctsk) is overexpressed in the white adipose tissue (WAT) of obese individuals. We herein characterized the
The Journal of clinical endocrinology and metabolism, 101(11), 4440-4448 (2016-11-05)
Patients with pheochromocytoma (pheo) show presence of multilocular adipocytes that express uncoupling protein 1 within periadrenal (pADR) and omental (OME) fat depots. It has been hypothesized that this is due to adrenergic stimulation by catecholamines produced by the pheo tumors.
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A better understanding of the processes influencing energy expenditure could provide new therapeutic strategies for reducing obesity. As the metabolic activity of the brown adipose tissue (BAT) and skeletal muscle is an important determinant of overall energy expenditure and adiposity
American journal of physiology. Endocrinology and metabolism, 305(2), E282-E292 (2013-05-30)
Obesity continues to be a global health problem, and thus it is imperative that new pathways regulating energy balance be identified. Recently, it was reported: (Hayashi K, Cao T, Passmore H, Jourdan-Le Saux C, Fogelgren B, Khan S, Hornstra I
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