662041

U-73343

A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

• 別名: U-73343, 1-[6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-2,5-pyrrolidinedione
• 実験式（ヒル表記法）: C₂₉H₄₂N₂O₃
• CAS番号: 142878-12-4
• 分子量: 466.66
• MDL番号: MFCD00211221
• UNSPSCコード: 51111800
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: off-white
• 溶解性: ethanol: 1 mg/mL; DMSO: 2 mg/mL; chloroform: 200 mg/mL
• 輸送温度: ambient
• 保管温度: 10-30°C
• SMILES記法: N5(C(=O)CCC5=O)CCCCCCN[C@@H]1[C@@]2([C@H]([C@H]3[C@H](CC2)c4c(cc(cc4)OC)CC3)CC1)C
• InChI: 1S/C29H42N2O3/c1-29-16-15-23-22-10-8-21(34-2)19-20(22)7-9-24(23)25(29)11-12-26(29)30-17-5-3-4-6-18-31-27(32)13-14-28(31)33/h8,10,19,23-26,30H,3-7,9,11-18H2,1-2H3/t23-,24-,25+,26+,29+/m1/s1
• InChI Key: CJHWFIUASFBCKN-ZRJUGLEFSA-N

詳細

詳細

A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

生物化学的／生理学的作用

Cell permeable: yes

Primary Target
Negative control of U-73122 in the inhibition of phospholipase C

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Irritant (B)

再構成

For storage in chloroform, aliquot into single use volumes, evaporate to dryness under a stream of nitrogen and freeze (-20°C). DMSO stocks solutions are stable for up to 6 months at -20°C.

その他情報

Tatrai, A., et al. 1994. Biochim. Biophys. Acta 1224, 595.
Bleasdale, J.E., et al. 1990. J. Pharmacol. Exp. Ther.255, 756.
Smith, R.J., et al. 1990. J. Pharmacol. Exp. Ther.253, 688.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable