572631

SU5402

InSolution, ≥95%, Inhibits the tyrosine kinase activity of FGFR1

• 別名: InSolution SU5402
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• フォーム: liquid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated (hygroscopic); protect from light
• 保管温度: −70°C

詳細

詳細

Inhibits the tyrosine kinase activity of FGFR1 (IC₅₀ = 10-20 µM in the presence of 1 mM ATP) by interacting with the catalytic domain of FGFR1. Also inhibits aFGF-induced phosphorylation of ERK1 and ERK2 (IC₅₀ = 10-20 µM). In contrast to SU4984, it acts only as a weak inhibitor of tyrosine phosphorylation of the PDGF receptor. Does not inhibit the phosphorylation of insulin receptor and exhibits no inhibitory effect on EGF receptor kinase.

包装

Packaged under inert gas

警告

Toxicity: Irritant (B)

物理的形状

A 10 mM (500 µg/169 µl) solution of SU5402 (Cat. No. 572630) in DMSO.

再構成

Following initial thaw, aliquot and freeze (-70°C).

その他情報

Mohammadi, M., et al. 1997. Science 276, 955.

法的情報

Not available for sale in the United States.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): 188.6 °F - (refers to pure substance)
• 引火点(℃): 87 °C - (refers to pure substance)