5.05016

CX546

• 別名: CX546, AMPA Positive Allosteric Modulator, CX546, CX-546, CX 546
• 実験式（ヒル表記法）: C₁₄H₁₇NO₃
• CAS番号: 215923-54-9
• 分子量: 247.29
• MDL番号: MFCD01860868
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• アッセイ: ≥98% (TLC)
• 品質水準: 100
• フォーム: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: off-white
• 溶解性: DMSO: soluble
• 保管温度: 2-8°C
• SMILES記法: N3(CCCCC3)C(=O)c1cc2c(cc1)OCCO2
• InChI: 1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2
• InChI Key: LJUNPHMOGNFFOS-UHFFFAOYSA-N

詳細

詳細

A positive allosteric modulator selective for the AMPA receptors. Used in studies related to Schizophrenia, neuroplasticity, Autism and neuronal differentiation.

生物化学的／生理学的作用

Primary Target
AMPA

警告

Toxicity: Standard Handling (A)

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

その他情報

Silverman, L., et al. 2013. Neuropharmacol.64, 268.
Peleg-Raibstein, D., et al. 2012. Curr. Antipsych.2012, 361.

Schitine, C., et al. 2012. Eur. J. Neurosci.35, 1672.
Lipina, T., et al. 2006. Neuropsychopharmacology.32, 745.
Arai, C., et al. 2004. Neurosci.123, 1011.
Nagarajan, N., et al. 2001. Neuropharmacol.41, 650.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable