210150

Cantharidic Acid

A potent inhibitor of protein phosphatase 2A (IC₅₀ = 50 nM).

• 別名: Cantharidic Acid, 5ʹ-3ʹ2,3-Dicarboxy-2,3-dimethyl-1,4-epoxycyclohexane, exo-1,6-Dicarboxy- endo-1,6-dimethyl-7-oxabicylco[2,2,1]heptane
• 実験式（ヒル表記法）: C₁₀H₁₄O₅
• CAS番号: 28874-45-5
• 分子量: 214.22
• MDL番号: MFCD00047137
• UNSPSCコード: 12352106
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: >95% (TLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: white
• 溶解性: warm ethanol: 10 mg/mL; DMSO: 25 mg/mL
• 輸送温度: ambient
• 保管温度: 10-30°C
• InChI: 1S/C10H14O5/c1-9(7(11)12)5-3-4-6(15-5)10(9,2)8(13)14/h5-6H,3-4H2,1-2H3,(H,11,12)(H,13,14)/t5-,6+,9-,10+
• InChI Key: NMTNUQBORQILRK-YUMGAWCOSA-N

詳細

詳細

A potent inhibitor of protein phosphatase 2A (IC₅₀ = 50 nM).

Inhibits protein phosphatase 2A (IC₅₀ = 50 nM).

生物化学的／生理学的作用

Cell permeable: no

Primary Target
PP2A

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 50 nM against protein phosphatase 2A

警告

Toxicity: Standard Handling (A)

再構成

Following reconstitution, aliqot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

その他情報

Zhang, Z., et al. 1996. Biochemistry35, 1606.
Li, Y.-M., and Casida, J.E. 1992. Proc. Natl. Acad. Sci. USA89, 11867.
Graziano, M.J., et al. 1988. Mol. Pharmacol.33, 706.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3