1.08262

トリフルオロ酢酸

for spectroscopy Uvasol^®

• 別名: TFA
• 化学式: CF₃COOH
• CAS番号: 76-05-1
• 分子量: 114.02
• Beilstein: 742035
• MDL番号: MFCD00004169
• UNSPSCコード: 12191502
• EC Index Number: 200-929-3
• NACRES: NA.03
• pH: 1 (10 g/L in H₂O)

特性

• 蒸気密度: 3.9 (vs air)
• 品質水準: 100
• 蒸気圧: 97.5 mmHg ( 20 °C)
• アッセイ: ≥99.8% (acidimetric)
• フォーム: liquid
• テクニック: UV/Vis spectroscopy: suitable
• 不純物: ≤10% Water (Karl Fischer)
• 蒸発残留物質: ≤0.005%
• 色: APHA: ≤10
• 透過率: 265 nm, ≥10.0%; 305 nm, ≥50.0%; 320 nm, ≥80.0%; 325 nm, ≥90.0%
• 屈折率: n20/D 1.3 (lit.)
• pH: 1 (10 g/L in H₂O)
• bp: 72.4 °C (lit.)
• mp: −15.4 °C (lit.)
• 溶解性: soluble 10 g/mL
• 密度: 1.489 g/mL at 20 °C (lit.)
• 保管温度: 2-30°C
• SMILES記法: OC(C(F)(F)F)=O
• InChI: 1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
• InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N

詳細

詳細

Accurate analytic results in UV/VIS and infrared spectroscopy depend on the use of very pure solvents for sample preparation. The Uvasol<TMSYMBOL></TMSYMBOL> solvents range has been specially designed for spectroscopy and other applications requiring solvents of the highest spectral purity. The refinement process allows a greater degree of security in applications and avoids misinterpretation of analytical results caused by traces of UV, IR and fluorescence contamination. Uvasol<TMSYMBOL></TMSYMBOL> solvents offer best UV transmittance. In all specifications the minimum transmittance for 5 typical wavelengths are identified.

アプリケーション

• Characterization of ribostamycin and its impurities using a nano-quantity analyte detector: This study examines ribostamycin and its impurities using a nano-quantity analyte detector and details a systematic comparison of three different aerosol detectors. The role of trifluoroacetic acid as a mobile phase additive enhances detection sensitivity and analytical precision, making it crucial for accurate impurity profiling and pharmaceutical quality control (Meng et al., 2024).


• Paradigm Shift: Major Role of Ion-Pairing-Dependent Size Exclusion Effects in Bottom-Up Proteomics Reversed-Phase Peptide Separations: This research highlights the critical role of trifluoroacetic acid in modifying the ion-pairing and size exclusion properties of peptides during reversed-phase separations in proteomics. The study provides a deeper understanding of the mechanisms influencing peptide behavior, which is essential for developing more effective analytical techniques (Yeung et al., 2024).


• New fabric phase sorptive extraction for nondestructive analysis of heritage textile samples: This paper introduces a novel fabric phase sorptive extraction method using trifluoroacetic acid among other solvents to analyze heritage textile samples nondestructively. This method demonstrates significant potential in cultural heritage preservation and forensic science by allowing detailed analysis without damaging the original artifacts (Tanasescu et al., 2024).


• Preparation and characterization of stationary phase gradients on C8 liquid chromatography columns: The study discusses the preparation and characterization of stationary phase gradients for chromatography columns, with trifluoroacetic acid used to adjust the pH and ionic strength of the mobile phase. This modification is shown to enhance the chromatographic separation of complex mixtures, proving vital for analytical and preparative scale separations (Cecil et al., 2024).


• Optimization of Cyanocobalamin (Vitamin B(12)) Sorption onto Mesoporous Superparamagnetic Iron Oxide Nanoparticles: This investigation utilizes trifluoroacetic acid in the synthesis and functionalization of nanoparticles for efficient vitamin B(12) sorption. The study explores the implications for targeted drug delivery systems and bioseparation, demonstrating the adaptability and effectiveness of these engineered nanoparticles (Flieger et al., 2024).

アナリシスノート

Assay (acidimetric): ≥ 99.8 %
Water (K. F.): ≤ 0.10 %
Colour number (Apha): ≤ 10
Evaporation residue: ≤ 0.005 %
UV-transmission (at 265 nm): ≥ 10.0 %
UV-transmission (at 305 nm): ≥ 50.0 %
UV-transmission (at 320 nm): ≥ 80.0 %
UV-transmission (from 325 nm): ≥ 90.0 %

その他情報

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

法的情報

UVASOL is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H314 - H332 - H412
• 注意書き: P261 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
• 保管分類コード: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 2
• 引火点(°F): 212.0 °F - Pensky-Martens closed cup
• 引火点(℃): > 100 °C - Pensky-Martens closed cup