1.05980

D-マンニトール

EMPROVE^® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, FCC, E 421

• 別名: マンニット
• 実験式（ヒル表記法）: C₆H₁₄O₆
• CAS番号: 69-65-8
• 分子量: 182.17
• Beilstein: 1721898
• MDL番号: MFCD00064287
• UNSPSCコード: 12352201
• E番号: E421
• EC Index Number: 200-711-8

特性

• 認証: BP; ChP; JP; Ph. Eur.; USP
• 品質水準: 500
• 法規制遵守: FCC
• 製品種目: EMPROVE^® ESSENTIAL
• 形状: fine powder
• 自己発火温度: 410 °C
• 有効性: 13500 mg/kg LD₅₀, oral (Rat)
• 品質: E 421
• 粒径: (see specification)
• pH: 5-7 (20 °C, 100 g/L in H₂O)
• bp: 290-295 °C/4 hPa
• mp: 167-170 °C (lit.)
• 溶解性: 213 g/L
• アプリケーション: liquid formulation; pharmaceutical; semi-solid formulation; solid formulation
• 保管温度: 2-25°C
• SMILES記法: OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
• InChI Key: FBPFZTCFMRRESA-KVTDHHQDSA-N

詳細

詳細

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

アプリケーション

Mannitol is widely used in pharmaceutical formulations and food applications, mainly as diluent and bulking agent in solid oral formulations such as tablets. For mannitols with DC properties or for a product specifically developed for wet granulation, please explore the Parteck^® range of products.

生物化学的／生理学的作用

糖アルコールの甘味物質です。甘味阻害試験に用いられます。

法的情報

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1