GLUT-8 is a glucose transporter facilitated by the regulation of insulin, binding cytochalasin B such that the orientation is glucose-inhibitive. In appearance, the transporter seems to be a dual-specific sugar transporter since fructose can also be inhibitive. GLUT-8 is expressed largely in the testis, where down-regulation is facilitated by estrogen. However, GLUT-8 is not highly expressed in testicular carcinoma. Lower levels of GLUT-8 are present in most other tissues.
特異性
Recognizes GLUT-8.
免疫原
An 11 amino acid sequence near the C-terminus of mouse Glut-8 (Doege et al. 2000; Carayannopoulos et al. 2000)
Epitope: C-terminus
アプリケーション
Research Category 細胞シグナル伝達
Research Sub Category インスリン/エネルギーシグナル伝達
Anti-GLUT-8 Antibody, C-terminus detects level of GLUT-8 & has been published & validated for use in IH(P).
品質
Evaluated by Immunohistochemistry in human kidney tissue Immunohistochemistry Analysis: 1:100 dilution of this lot detected GLUT-8 in human kidney tissue.
ターゲットの説明
Approx. 50 kDa
関連事項
Replaces: AB3140
物理的形状
ImmunoAffinity Purified
Format: Purified
Liquid in PBS with 0.1% BSA.
保管および安定性
Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles.
アナリシスノート
Control Human kidney tissue.
その他情報
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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