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Merck

P-055

Supelco

Propranolol hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

実験式(ヒル表記法):
C16H21NO2·HCl
CAS番号:
分子量:
295.80
EC Number:
UNSPSCコード:
41116107
NACRES:
NA.24

グレード

certified reference material

形状

liquid

特徴

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

メーカー/製品名

Cerilliant®

濃度

1.0 mg/mL in methanol (as free base)

テクニック

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

アプリケーション

clinical testing

フォーマット

single component solution

保管温度

−20°C

SMILES記法

Cl.CC(C)NCC(O)COc1cccc2ccccc12

InChI

1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H

InChI Key

ZMRUPTIKESYGQW-UHFFFAOYSA-N

遺伝子情報

詳細

A certified reference solution suitable for use as starting material in calibrators and controls for LC/MS or GC/MS testing methods in clinical and diagnostic testing, urine drug testing, forensic analysis, or clinical toxicology. Propranolol is a sympatholytic non-selective beta blocker used to treat a variety of medical conditions including hypertension, anxiety and panic. The drug is sold under numerous brand names such as Inderal®, Avlocardyl, Deralin, and Dociton.

アプリケーション

<ul>
<li><strong>Propranolol hydrochloride solution for infantile hemangioma:</strong>Liposomal formulations of propranolol hydrochloride have been developed for the treatment of infantile hemangioma, offering a targeted therapeutic approach in pediatric dermatology (Nifli et al., 2024).</li>
<li><strong>Propranolol hydrochloride:</strong> Research on the percutaneous absorption of solvent-deposited propranolol hydrochloride across different skin layers provides insights into its properties like it can be used as a function of dose and ionization state and as a calibration standard (Tonnis et al., 2024).</li>
</ul>

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Inderal is a registered trademark of Cranford Pharmaceuticals, LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

ピクトグラム

FlameSkull and crossbonesHealth hazard

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

ターゲットの組織

Eyes

保管分類コード

3 - Flammable liquids

WGK

WGK 1

引火点(°F)

49.5 °F - closed cup

引火点(℃)

9.7 °C - closed cup


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

消防法

第4類:引火性液体
アルコール類
危険等級II

Jan Code

P-055-1ML:4548174003923
P-055-CC:


試験成績書(COA)

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この製品を見ている人はこちらもチェック

What doesn't kill may not make you stronger. β-blockers for asthma.
Shamsah Kazani et al.
American journal of respiratory and critical care medicine, 187(12), 1281-1281 (2013-06-19)
Philip M Short et al.
American journal of respiratory and critical care medicine, 187(12), 1308-1314 (2013-04-19)
Unblinded studies have shown improvements in airway hyperresponsiveness with chronic nadolol in steroid-naive patients with asthma. To assess the effects of chronic nonselective β-blockade as add-on to inhaled corticosteroids (ICS) in patients with asthma. A double-blind randomized placebo-controlled crossover trial
Jun Zhang et al.
Rapid communications in mass spectrometry : RCM, 27(7), 731-737 (2013-03-16)
Multiplexed liquid chromatography (LC) coupled with multiple-injection-chromatogram acquisition has emerged as the method of choice for high-speed discovery bioanalysis, because it significantly reduces injection-to-injection cycle time while maintaining the chromatography quality. Historically, systems utilizing this approach had been custom built
[Propanolol effective treatment for laryngo-tracheal hemangioma].
Markus Granholm et al.
Lakartidningen, 110(19-20), 947-948 (2013-06-12)
Oral propranolol versus placebo for retinopathy of prematurity: a pilot, randomised, double-blind prospective study.
Imad R Makhoul et al.
Archives of disease in childhood, 98(7), 565-567 (2013-05-02)

資料

This article highlights the impact that sample matrix effects can have on LC/MS response and discusses two novel approaches to reduce it.

Learn about Supel™ BioSPME C18 high-throughput devices to determine plasma protein binding and decrease the sample preparation time to less than an hour.

Comparative analysis of Supel™ BioSPME 96-Pin device with a rapid equilibrium dialysis technique for accuracy of measured values, sample cleanliness, and workflow time in drug protein binding.

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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