E-075

Estrone solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 実験式（ヒル表記法）: C₁₈H₂₂O₂
• CAS番号: 53-16-7
• 分子量: 270.37
• MDL番号: MFCD00003620
• UNSPSCコード: 41116107
• PubChem Substance ID: 329798986
• NACRES: NA.24

特性

• グレード: certified reference material
• 形状: liquid
• 特徴: Snap-N-Spike^®/Snap-N-Shoot^®
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• 濃度: 1.0 mg/mL in methanol
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: clinical testing; clinical testing
• フォーマット: single component solution
• 保管温度: −20°C
• SMILES記法: CC12CCC3C(CCc4cc(O)ccc34)C1CCC2=O
• InChI: 1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1
• InChI Key: DNXHEGUUPJUMQT-CBZIJGRNSA-N
• 遺伝子情報: human ... ESR1(2099)

詳細

詳細

A precursor of estradiol, estrone is monitored in serum or plasma by LC-MS/MS or GC/MS to assess and diagnose developmental abnormalities, enzyme inactivity or deficiency, polycystic ovary syndrome (PCOS), or hormone replacement therapy in women.

アプリケーション

• Fluconazole solution for yeast infection treatment: Fluconazole is extensively utilized for its efficacy against yeast infections, specifically vulvovaginal candidiasis. It operates by inhibiting the synthesis of ergosterol, crucial for fungal cell membrane integrity, thereby exerting its antifungal effects (Picheta et al., 2024).


• Antifungal medication in systemic candidiasis: Fluconazole solution is critical in treating systemic candidiasis, offering a potent antifungal mechanism that disrupts the fungal cell membrane′s ergosterol content, essential for maintaining fungal cell viability (Dettlaff et al., 2024).


• Fluconazole in vitro antifungal activity assay development: Fluconazole is utilized in the development of in vitro antifungal activity assays, which are crucial for screening potential antifungal agents and assessing their efficacy against various fungal pathogens (Teba et al., 2024).

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370
• 注意書き: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• ターゲットの組織: Eyes,Central nervous system
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 2
• 引火点(°F): 49.5 °F - closed cup
• 引火点(℃): 9.7 °C - closed cup