C-907

クロナゼパム 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 実験式（ヒル表記法）: C₁₅H₁₀ClN₃O₃
• CAS番号: 1622-61-3
• 分子量: 315.71
• EC Number: 200-659-6
• MDL番号: MFCD00057746
• UNSPSCコード: 41116107
• PubChem Substance ID: 329775195
• NACRES: NA.24

特性

• グレード: certified reference material
• 品質水準: 300
• 形状: liquid
• 特徴: Snap-N-Spike^®/Snap-N-Shoot^®
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• 濃度: 1.0 mg/mL in methanol
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: clinical testing
• フォーマット: single component solution
• 保管温度: −20°C
• SMILES記法: [O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3Cl)c2c1
• InChI: 1S/C15H10ClN3O3/c16-12-4-2-1-3-10(12)15-11-7-9(19(21)22)5-6-13(11)18-14(20)8-17-15/h1-7H,8H2,(H,18,20)
• InChI Key: DGBIGWXXNGSACT-UHFFFAOYSA-N
• 遺伝子情報: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

詳細

詳細

クロナゼパムはクロノピンおよびリボトリールなどの商標名で販売される、強力で長時間作用型のベンゾジアゼピンであり、抗不安、抗けいれん、筋弛緩、および催眠作用を有しています。クロナゼパムはてんかん治療の目的で処方されます。このCertified Snap-N-Spike^®Solutionは、法医学分析、臨床毒性学、尿中薬物検査、または疼痛処方モニタリングのためのGC/MSまたはLC/MSの用途に適しています。

アプリケーション

• Clonazepam research solution: Research on chemometric methods for determining the dissociation constants of benzodiazepine derivatives, including clonazepam, showcases its critical role in improving the precision of pharmaceutical analyses. This method enhances the understanding of clonazepam′s interactions in various conditions, aiding in its application in scientific research and drug formulation (Shayesteh et al., 2015).


• High-purity clonazepam liquid for scientific study: A study employing solubility prediction models for drugs, including clonazepam, in mixed solvents provides significant insights into its solubility behavior. This knowledge is crucial for optimizing drug formulations and enhancing bioavailability in pharmaceutical preparations (Jouyban et al., 2011).


• Clonazepam as a GABA receptor agonist in lab experiments: An investigation into multibenzodiazepine determination in human plasma emphasizes the importance of clonazepam in clinical and pharmaceutical research, particularly its role in affecting GABA receptors, crucial for understanding its pharmacological impacts (Borges et al., 2009).

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370
• 注意書き: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• ターゲットの組織: Eyes,Central nervous system
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 2
• 引火点(°F): 49.5 °F - closed cup
• 引火点(℃): 9.7 °C - closed cup