860470P

1-deoxysphingosine

Avanti Research^™ - A Croda Brand 860470P, powder

• 別名: 1-deoxysphingosine (m18:1)
• 実験式（ヒル表記法）: C₁₈H₃₇NO
• CAS番号: 193222-34-3
• 分子量: 283.49
• MDL番号: MFCD22416646
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• フォーム: powder
• 包装: pkg of 1 × 1 mg (860470P-1mg); pkg of 1 × 10 mg (860470P-10mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand 860470P
• 脂質タイプ: bioactive lipids; sphingolipids
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: C[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI Key: ZREXGWPJFRJAJU-SWESGNQDSA-N

詳細

詳細

1-deoxysphingosine (1-deoxySO) has a (4E) double bond in its structure and is synthesized by the catabolism of 1-deoxyceramide in the presence of ceramidase enzyme.[1] It is an unsaturated deoxy-sphingoid base.[2]

アプリケーション

1-deoxysphingosine may be used for the complex preparation with bovine serum albumin for cytotoxicity testing of MN9D dopaminergic neuroblastoma cell line[3] and dorsal root ganglion neurons cultures.[2] It may also be used as a standard for quantification of spingolipids from human plasma samples by liquid chromatography electrospray ionization tandem mass spectrometry (LC−ESI−MS/MS).[4]

生物化学的／生理学的作用

1-deoxysphingosine levels are elevated in lymphoblasts in hereditary sensory neuropathy type 1 (HSAN1) disorder.[2]

包装

5 mL Amber Glass Screw Cap Vial (860470P-10mg)

5 mL Amber Glass Screw Cap Vial (860470P-1mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3