760927

Poly(ethylene glycol), 16 acetylene dendron, generation 3

average M_n 8,000

• 別名: Bis-MPA poly(ethylene glycol), Bis[2,2-bis(hydroxymethyl)propanoic acid] PEG, Dendron functionalized PEG acetylene, generation 3, PEG-6000, PFD-G3-PEG6k-Acetylene
• UNSPSCコード: 12162002

特性

• 詳細: acetylene surface groups
• フォーム: solid
• 分子量: PEG average M_n 6,000 (n~130, esterified with 16 acetylene groups); M_n 7500-9500 (by NMR); average M_n 8,000
• 特徴: generation 3
• 表面基数: 16
• mp: 43-47 °C
• 官能基: alkyne

詳細

詳細

Dendrimers and dendrons are symmetrically branched polymer structures that possess a well-defined spatial distribution of functional groups.[1] Dendrimers are chemically modified by attaching poly ethylene glycol (PEG) molecule to increase its solubility and prolong circulation half-life.[2]“Clickable groups”, such as primary acetylenes, are introduced to the mono dispersed dendritic structures, using “click” chemistry. These acetylene groups, attached to Bis-MPA based dendrons, allow it to form the conjugates with bioactive moieties such as carbohydrate, fluorescent dyes, disaccharides etc.[1][3][4]

アプリケーション

The proposed uses are

• as an efficient drug delivery system.
• In vitro toxicological studies
• In vivo via radionuclide labeling and optical imaging
• Biosensors
• Dip pen nanolithography [1][4]

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): No data available
• 引火点(℃): No data available