638013

4-Diphenylphosphanylbenzoic acid, 2-(trimethylsilyl)ethyl ester solution

0.5 M in THF

• 実験式（ヒル表記法）: C₂₄H₂₇O₂PSi
• CAS番号: 566190-45-2
• 分子量: 406.53
• MDL番号: MFCD07369722
• UNSPSCコード: 12352108
• PubChem Substance ID: 24882904

特性

• 反応適合性: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• 濃度: 0.5 M in THF
• 密度: 0.925 g/mL at 25 °C
• 官能基: phosphine
• SMILES記法: C[Si](C)(C)CCOC(=O)c1ccc(cc1)P(c2ccccc2)c3ccccc3
• InChI: 1S/C24H27O2PSi/c1-28(2,3)19-18-26-24(25)20-14-16-23(17-15-20)27(21-10-6-4-7-11-21)22-12-8-5-9-13-22/h4-17H,18-19H2,1-3H3
• InChI Key: QTYUNPJLGFKKRV-UHFFFAOYSA-N

詳細

アプリケーション

以下の反応物質です。

• アルケン類の合成
• アルデヒド類のメチル化
• 光延反応

4-Diphenylphosphanyl-benzoic acid 2-trimethylsilanyl-ethyl ester (DPPBE) was developed as an efficient alternative to triphenylphosphine in the Mitsunobu reaction since the phosphine oxide formed during the reaction can be easily removed during workup.

安全性情報

• ピクトグラム: GHS02,GHS08,GHS07
• シグナルワード: Danger
• 危険有害性情報: H225,H319,H335,H351
• 注意書き: P210 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• 危険有害性の分類: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 補足的ハザード: EUH019
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 3
• 引火点(°F): -4.0 °F - closed cup
• 引火点(℃): -20 °C - closed cup