464155

[3aR-[2(3'aR*,8'aS*),3'aβ,8'aβ]]-(+)-2,2'-メチレンビス[3a,8a-ジヒドロ-8H-インデノ[1,2-d]オキサゾール]

98%

• 実験式（ヒル表記法）: C₂₁H₁₈N₂O₂
• CAS番号: 180186-94-1
• 分子量: 330.38
• MDL番号: MFCD06797115
• UNSPSCコード: 12352005
• PubChem Substance ID: 24870145
• NACRES: NA.22

特性

• アッセイ: 98%
• 光学活性: [α]22/D +353°, c = 3.7 in chloroform
• mp: 204-206 °C (lit.)
• SMILES記法: C1[C@@H]2OC(CC3=N[C@H]4[C@@H](Cc5ccccc45)O3)=N[C@H]2c6ccccc16
• InChI: 1S/C21H18N2O2/c1-3-7-14-12(5-1)9-16-20(14)22-18(24-16)11-19-23-21-15-8-4-2-6-13(15)10-17(21)25-19/h1-8,16-17,20-21H,9-11H2/t16-,17-,20+,21+/m0/s1
• InChI Key: BDHSVQLSNIGJNC-ZCLUNYJNSA-N

詳細

アプリケーション

[3aR-[2(3′aR*,8′aS*),3′aβ,8′aβ]]-(+)-2,2′-Methylenebis[3a,8a-dihydro-8H-indeno[1,2-d]oxazole] is a C₂ symmetric chiral ligand based on bis(oxazoline) moiety, which can be used in enantioselective catalysis. It easily forms bidentate coordination complexes due to the strong affinity of the oxazoline nitrogen for various metals. Copper complex of this chiral ligand can be utilized as a reusable catalyst in the cyclopropanation reaction between styrene and ethyl diazoacetate.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves