393711

2′,3′-Dideoxy-3′-fluorouridine

95%

• 別名: 3′-Fluoro-2′,3′-dideoxyuridine
• 実験式（ヒル表記法）: C₉H₁₁FN₂O₄
• CAS番号: 41107-56-6
• 分子量: 230.19
• Beilstein: 6064366
• EC Number: 415-360-8
• MDL番号: MFCD00192015
• UNSPSCコード: 12352100
• PubChem Substance ID: 24864537
• NACRES: NA.22

特性

• アッセイ: 95%
• 光学活性: [α]20/D +10.5°, c = 0.5 in 1 M NaOH
• mp: 184-188 °C (lit.)
• SMILES記法: OC[C@H]1O[C@H](C[C@@H]1F)N2C=CC(=O)NC2=O
• InChI: 1S/C9H11FN2O4/c10-5-3-8(16-6(5)4-13)12-2-1-7(14)11-9(12)15/h1-2,5-6,8,13H,3-4H2,(H,11,14,15)/t5-,6+,8+/m0/s1
• InChI Key: BKIUEHLYJFLWPK-SHYZEUOFSA-N

詳細

詳細

2′,3′-Dideoxy-3′-fluorouridine (3′-fluoro-2′,3′-dideoxyuridine, FddUrd) is a fluorinated pyrimidine nucleoside analog of uridine. It has been studied extensively for its potential use as an antiviral agent against HIV.[1][2][3]

アプリケーション

2′,3′-Dideoxy-3′-fluorouridine can be used as a starting material in the synthesis of:

• 3′-fluoro 2′,3′-dideoxynucleoside analogs for in vitro antiviral activity studies.[4]
• 3′-fluoro deoxyuridine monophosphate analogs as potential anti parasites.[5]

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Warning
• 危険有害性情報: H341
• 注意書き: P281
• 危険有害性の分類: Muta. 2
• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves