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Merck

TGFB2

transforming growth factor, beta 2

別名:
LDS4, TGF-beta2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(7042) Summary: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]
  • Mouse(21808) transforming growth factor, beta 2
  • Rat(81809) transforming growth factor, beta 2
  • dog(488596) transforming growth factor, beta 2
  • Zebrafish(369194) transforming growth factor, beta 2
  • domestic guinea pig(100720726) transforming growth factor, beta 2
  • chicken(421352) transforming growth factor, beta 2
  • cow(534069) transforming growth factor, beta 2
  • domestic cat(101093414) transforming growth factor, beta 2
  • sheep(554322) transforming growth factor, beta 2
  • Domestic Rabbit(100009371) transforming growth factor, beta 2
  • naked mole-rat(101707457) transforming growth factor, beta 2

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ELISA

製品番号
詳細
Species
Human TGF-β 2 ELISA Kit, for serum, plasma, and cell culture supernatants,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-TGFB2 antibody produced in rabbit, affinity isolated antibody,
交差性
bovine, dog, horse, human, mouse, pig, rabbit, rat, sheep
アプリケーション
western blot
Anti-TGF β2, C-Terminal antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry
ANTI-TGF BETA 2(C-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-Transforming Growth Factor-β, pan antibody produced in rabbit, IgG fraction of antiserum, lyophilized powder,
交差性
amphibian, human, pig
アプリケーション
microarray
neutralization

western blot

Proteins

製品番号
詳細
Species
トランスフォーミング増殖因子-β2 ヒト, TGF-β2, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture,
Species
human
Transforming Growth Factor-β2 Protein, Recombinant human, Transforming Growth Factor-beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation & differentiation of normal & transformed cells.,
Species
human
トランスフォーミング増殖因子-β2 ブタ血小板由来, powder, suitable for cell culture,
Species
トランスフォーミング増殖因子-β2 ヒト, TGF-β2, recombinant, expressed in NSO cells, powder, suitable for cell culture,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human TGFB2,
Species
human
MISSION® esiRNA, targeting mouse Tgfb2,
Species
mouse