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由来生物
rabbit
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
antigen 47 kDa
化学種の反応性
mouse, rat, human
濃度
~1 mg/mL
テクニック
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
NCBIアクセッション番号
UniProtアクセッション番号
アプリケーション
research pathology
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... TGFB2(7042)
詳細
Anti-TGF β2 Antibody detects endogenous levels of total TGF β2 protein.
Transforming growth factor-β2 (TGFB2) gene codes for the transforming growth factor β2 (TGFβ2).( β (TGF-β) protein superfamily. TGFB2 gene is mapped to human chromosome 1q41.
免疫原
The antiserum was produced against synthesized peptide derived from human TGF beta2.
Immunogen Range: 361-410
Immunogen Range: 361-410
アプリケーション
Anti-TGF β2, C-Terminal antibody produced in rabbit has been used in western blotting.
生物化学的／生理学的作用
Transforming growth factor-β2 (TGFB2) protein plays a key role in transforming growth factor-β (TGF-β) signaling pathway. It aids in binding several TGF-β receptors to recruit and stimulate the others against decapentaplegic homolog SMAD protein family. TGF-β2 is involved in the proliferation and metastasis of glioma cells. It is implicated in metabolic syndrome (MetS). Single-nucleotide polymorphisms (SNPs) in TGFB2 are also associated with end-stage renal disease and conotruncal heart defects.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Mustafa Becerikli et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 40(8), 1810-1826 (2021-11-15)
Bone regeneration and fracture healing are impaired in diabetic patients due to defective functions of associated cells. Thus, the search for molecular causes and new treatment strategies are of particular clinical relevance. We investigated the gene expression profile of bones
Eugene Lin et al.
Scientific reports, 7(1), 13589-13589 (2017-10-21)
The transforming growth factor-β (TGF-β) signaling pathway and its relevant genes have been correlated with an increased risk of developing various hallmarks of metabolic syndrome (MetS). In this study, we assessed whether the TGF-β signaling pathway-associated genes of SMAD family
Kejuan Song et al.
Oncology reports, 39(5), 2063-2070 (2018-03-08)
Ovarian cancer is a highly metastatic malignancy and a leading cause of cancer-related death in postmenopausal women. Emodin is a natural anthraquinone isolated from several traditional Chinese medicines including Rhubarb and Polygonum cuspidatum. Recently, emodin was demonstrated to reduce the growth
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