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Merck

SLC6A4

solute carrier family 6 (neurotransmitter transporter), member 4

別名:
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
Species:
UniProtKB ID:
遺伝子ID:
  • Human(6532) Summary: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
  • Mouse(15567) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Rat(25553) solute carrier family 6 (neurotransmitter transporter), member 4
  • domestic guinea pig(100135619) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • naked mole-rat(101705584) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Domestic Rabbit(100340600) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Domestic Rabbit(100351801) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • dog(491184) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • domestic cat(101091163) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Horse(100053721) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • cow(282365) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • chicken(404747) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

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Small Molecule - Antagonist

製品番号
詳細
Species
N-エチルマレイミド, purum p.a., ≥99.0% (HPLC),
Species
human
N-エチルマレイミド, BioUltra, ≥99.0% (HPLC),
Species
human
4-ベンジルピリジン, 98%,
Species
rat
N-エチルマレイミド, BioXtra, ≥98% (HPLC),
Species
human
ジフェニル-4-ピリジルメタン, 99%,
Species
rat

Antibodies

製品番号
詳細
交差性
アプリケーション
抗セロトニントランスポーター (N-末端) ウサギ宿主抗体, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Anti-Serotonin (5-HT) Transporter (602-622) Rabbit pAb, lyophilized, Calbiochem®,
交差性
mouse, rat
アプリケーション
抗SLC6A4/5HTT/SERT抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
Anti-SLC6A4 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
交差性
bovine, human, mouse, rat
アプリケーション
ELISA
flow cytometry

immunofluorescence
Anti-SLC6A4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence

Small Molecule - Inhibitor

製品番号
詳細
Species
エスシタロプラム シュウ酸塩, ≥98% (HPLC), powder,
Species
human
パロキセチン 塩酸塩 ヘミ水和物, ≥98% (HPLC), powder,
Species
human
ダポキセチン 塩酸塩, ≥98% (HPLC),
Species
human
フルオキセチン 塩酸塩 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
シタロプラム 臭化水素酸塩 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human SLC6A4,
Species
human