SAB2502028

Anti-SLC6A4 (C-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• 別名: 5-HTT, 5-HTTLPR, 5HTT, HTT, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: goat
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 交差性: rat, bovine, human, mouse
• テクニック: ELISA: suitable; flow cytometry: suitable; immunofluorescence: suitable
• UniProtアクセッション番号: P31645
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SLC6A4(6532)

詳細

詳細

Solute carrier family 6 member 4 (SLC6A4) is also known as 5-hydroxytryptamine transporter (5-HTT). It is an integral membrane protein, which is mapped to human chromosome 17q11.2. The encoded protein is a member of the SLC6 (solute carrier family 6) gene family and is mainly expressed in brain and blood cells.

免疫原

Peptide with sequence C-KERIIKSITPETPT, from the C-terminal region of the protein sequence according to NP_001036.1

生物化学的／生理学的作用

Solute carrier family 6 member 4 (SLC6A4) catalyzes the transport of neurotransmitter serotonin from the synaptic space into presynaptic neurons. It plays a vital role in mood and anxiety regulation. Mutation in the gene may alter the expression of serotonin (5HT) in the synaptic cleft, which ultimately leads to schizophrenia. Allelic variations in the gene increase the risk of susceptibility to autism and rigid-compulsive behaviors.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

20mM Tris（pH 7.3）、150mM NaCl、0.02％ アジ化ナトリウム、0.5％ ウシ血清アルブミン含有）を含む溶液中に0.5 mg/mLの濃度で提供されます。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable