コンテンツへスキップ
Merck

SCNN1A

sodium channel, non-voltage-gated 1 alpha subunit

別名:
BESC2, ENaCa, ENaCalpha, SCNEA, SCNN1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(6337) Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]
  • Mouse(20276) sodium channel, nonvoltage-gated 1 alpha
  • Rat(25122) sodium channel, nonvoltage-gated 1 alpha
  • cow(282348) sodium channel, non-voltage-gated 1 alpha subunit
  • dog(403650) sodium channel, non-voltage-gated 1 alpha subunit
  • domestic cat(101091122) sodium channel, non-voltage-gated 1 alpha subunit
  • chicken(396050) sodium channel, non-voltage-gated 1 alpha subunit
  • naked mole-rat(101700410) sodium channel, non-voltage-gated 1 alpha subunit
  • sheep(443488) sodium channel, non-voltage-gated 1 alpha subunit
  • domestic guinea pig(100135613) sodium channel, nonvoltage-gated 1 alpha

Custom & Knockdown Gene Products

Small Molecule - Antagonist

製品番号
詳細
Species
リドカイン, powder,
Species
rat, human
リドカイン, analytical standard,
Species
rat, human
ラモトリジン, ≥98%, powder,
Species
rat, human
5-(N,N-ジメチル)アミロライド 塩酸塩, ,
Species
rat, mouse, human
カルバマゼピン, meets USP testing specifications,
Species
rat, human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Epithelial Sodium Channel-α Antibody, Chemicon®, from rabbit,
交差性
rat
アプリケーション
western blot
Anti-SCNN1A antibody produced in rabbit, 1 mg/mL, affinity isolated antibody,
交差性
mouse, rat
アプリケーション
immunohistochemistry
western blot
Monoclonal Anti-ENaC alpha antibody produced in mouse, clone 2G4,
交差性
mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-SCNN1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Monoclonal Anti-ENaC alpha antibody produced in mouse, clone 14E10,
交差性
mouse, rat
アプリケーション
immunohistochemistry
western blot

Small Molecule - Blocker

製品番号
詳細
Species
トリアムテレン, ≥99%,
Species
human
トリアムテレン, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
トリアムテレン, United States Pharmacopeia (USP) Reference Standard,
Species
human
トリアムテレン, European Pharmacopoeia (EP) Reference Standard,
Species
human
トリアムテレン, British Pharmacopoeia (BP) Reference Standard,
Species
human

Small Molecule - Inhibitor

製品番号
詳細
Species
ベンザミル 塩酸塩 水和物, ≥98% (HPLC),
Species
mouse, rat, human
フェナミル メタンスルホン酸塩, solid,
Species
mouse, rat, human
5-(N-メチル-N-イソブチル)アミロライド, ≥98% (TLC), powder,
Species
mouse, rat, human
リドカイン, powder,
Species
rat, human
リドカイン, analytical standard,
Species
rat, human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Scnn1a,
Species
mouse
MISSION® esiRNA, targeting human SCNN1A,
Species
human